ABSTRACT The aims of this research work were to formulate artemether-loaded self emulsifying drug delivery system (SEDDS), evaluate some of its in vitro and in vivo properties, and prevent drug precipitation through supersaturation approach. The solubility of artemether (ARM) in various oils, surfactants and cosurfactants was determined using the equilibrium solubility method. Vehicles such as Triacetin®, Labrasol® and Transcutol P® were selected as components of the formulation due to the...
ABSTRACT The proliferation of abandoned surface excavations in the Benue Rift not only contributes to land degradation and landscape disruption but also results in loss of economic deposits, dearth of mining data and generation of unprotected spoils with known potential to contaminate ground and surface water sources. This study employed field description and measurements, laboratory testing and numerical simulation techniques to evaluate some derelict barite fields in the rift with the aim o...
Abstract Melon snack was produced by the conventional method in which melon and ground yeast was used as the main ingredients, in addition to other ingredients. The proportion of melon and ground yeast were varied while the other ingredients were kept constant so as to determine the best combination that would give a good quality snack. The combination of 70% melon, 8.81% ground yeast and 21.19% other ingredients was used as the control sample, since this combination formed the best dough nee...
Abstract The frequency of accidental discharge of oil into aquatic environment has presented a significant threat to marine biota with related adverse effects on the supply of products and services of importance to human cultures. This threat of economic and environmental devastation led to the development of a number of monitoring and clean-up alternatives such as remote sensing and chemical dispersants, respective. This study proposed a new possible research direction in marine oil spill mo...
ABSTRACT A questionnaire and observational study were randomly conducted on 204 houses to acquire information on different sewage disposal methods used in Enugu metropolis, and to investigate the impact of the sewage disposal methods on available water supplies. The results obtained show that 51% of the resident’s wells are located at a distance less than 9m from the toilets. Samples from 21 different locations in the area were analyzed and studied in order to assess the quality of the grou...
ABSTRACT Stabilized yoghurt samples were produced by reconstituting powdered milk in water along with sugar and 0, 0.5 and 1.0 % concentrations of carboxyl methyl cellulose (CMC), Corn starch and gum acacia before fermentation. The yoghurt samples were either produced as short set yoghurt by incubating at 42 oC for 5 hours or incubating at 30 ± 2 oC (room conditions) for 24 hours as long set yoghurt. Samples were analyzed at intervals of 1 h for 5 h for the short set yoghurt and at intervals...
TABLE OF CONTENTS Title Page i Certificate of Approval ii Dedication iii Acknowledgment iv Abstract v Table of contents vi 1. FRACTIONAL ORDER CALCULUS 2. FUNCTIONS OF FRACTIONAL CALCULUS 2.1 The Gamma function 3 2.2 The Beta Function 5 2.3 The Mittag-Leffler Function 5 2.4 Laplace Transform 7 2.5 The Convolution Theorem 9 2.6 Riemann-Liouville Fractional integral 10 2.7 Riemann-Liouville Fractional derivative 13 2.8 The Caputo’s Fractional Derivative 14 2.9 Laplace Transform of Fractional ...
ABSTRACT HIV/AIDS is still of major public health concern. With no vaccine in sight, it is only necessary to take a look at the sexual behaviors and practices of people living with HIV/AIDS. This study was to determine the sexual behaviors of people living with HIV attending ART clinic at District Hospital, Agbani, Nkanu-west local government area, Enugu state. METHODOLOGY: This was a descriptive cross sectional study. A systematic random sampling method was used to select 321 participants. D...
ABSTRACT Replication is the repetition of the treatments under investigation to different experimental unit. Replication is essential for obtaining a valid estimate of the experimental error and to a greater extent, increasing the precision of estimating the pairwise difference among the treatment effects. It is on this note that when full replication (replication of cube and star point) is made, there exists need for optimal replication for the purpose of minimizing biasedness. Some variatio...
ABSTRACT A mathematical model consisting of a set of two coupled non-linear reaction diffusion equations has been developed. The model is based on the chemical kinetics of transesterification for biodiesel production using irreversible and non-catalytic conditions. Employing the hyperbolic tangent approach, an exact analytical solution for the travelling-waves of a finite series form was found. The wave number and the speed of the wave were determined. Furthermore,physical interpretations wer...
Abstract These findings documented the physical, chemical and heavy metal contents in leachate, borehole water, surface stream, treated water and soil samples around the municipal solid waste dumpsite at Uyo metropolis, Akwa-Ibom State, Nigeria. Samples were collected during the wet and dry seasons 2010/2011. The samples were analysed for the following parameters: heavy metals (Fe, Cu, Mn, Zn, Cr, Cd, Pb), anions (PO3 4,SO2- 4,Cl- , NO3, NH+ 4-N), essential metals (Na, K, Ca, Mg), total disso...
ABSTRACT Production of carbon black from novel sources like spent automobile tyre, anthracite coal, furnace soot and graphite rod and subsequent use in the production of offset printing inks has been investigated. Carbon black from these sources were obtained by pyrolysis of shredded spent tyre and coal samples at 750-900o C in an electrical furnace, isolation of furnace carbon black and graphite rod from dry cell, drying and pulverization of the resulting samples. Acid demineralization of th...
ABSTRACT Reservoir and bottom hole temperatures from seventy wells in the Eastern Niger Delta suggests that two leg dogleg geothermal patterns characterize the geothermal gradients pattern of the Central Swamp and the Coastal Swamp in contrast to the single gradient patterns seen in the Shallow Offshore. In the shallow/continental sections in the Niger Delta, geothermal gradients vary between 10 - 18 o C/Km onshore, increasing to about 24 o C/Km seawards. In the deeper (marine/parallic) secti...
ABSTRACT Trypanosomiasis is a vector-borne parasitic disease, transmitted to animals by tsetse fly (Glossina genus) bites. The human type causes sleeping sickness in man while animal type causes nagana in animals. The aim of this study is to characterize trypanosomes isolated from dogs and cattle in Jos South Abattoir. Isolated trypanosomes were subjected to polymerase chain reaction using kin primers targeting internal transcribed spacer 1 (ITS1) of ribosomal deoxyribonucleic acids. The PCR ...
Abstract Several authors have developed statistical procedures for testing whether two models are similar. In this work, we not only present the notion of equivalence but also extend this to a measure of predictive ability of a time series following a stationary self-exciting threshold autoregressive (SETAR) process. A proposition and a lemma were used to join the structure of the predictability measure to the coefficients and sample autocorrelation of the SETAR process. Illustrative examples...