Medical & Health Sciences

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Medical & Health Sciences Research Papers/Topics

Do Frequent Antenatal Care Visits Ensure Access and Adherence to Intermittent Preventive Treatment of Malaria in Pregnancy in an Urban Hospital in South West Nigeria?

ABSTRACT The relationship of antenatal clinic (ANC) attendance and factors that could affect intermittent preventive treatment (IPT) uptake among 339 parturient women was examined. Respondents were enrolled over a period of three months in a secondary healthcare facility within 24 hours of delivery. Demographic details, delivery and antenatal history, insecticide treated net (ITN) use, and history of IPTp-Sulfadoxine-Pyrimethamine (SP) use in the index pregnancy were recorded. Finger and heel...

Anti-Inflamatory and Analgesic Activities of Securidaca longepedunculata Fers (Polygalaceae) Leaf and Stem Bark Methanolic Extract

ABSTRACT Securidaca longepedunculata Fers (Polygalaceae) is commonly used in many parts of Africa for the treatment of rheumatic conditions, fever, headache and various other inflammatory based diseases. The present study was carried out to evaluate the anti-inflammatory and analgesic activity of Securidaca longepedunculata leaf and stem bark methanol extracts using animal model. The anti-inflammatory activity of the methanolic extracts were evaluated using carrageenan induced paw edema in r...

Human T-Cell Lymphotropic Virus Types I and II Infections in Mother-Child Pairs in Nigeria

A community-based survey to determine the prevalence of human T-cell Iymphotropic type I (HTLV-I) and type II (HTLV-II) virus infections in mothers and children in south-western Nigeria was carried out using blood samples collected in 1993. A multistage cluster, random sampling procedure was used to select 460 mother-child pairs (476 children because there were 16 sets of twills) from 14 enumeration areas. A commercially available, whole HTLV-I lysate antigen-based ELISA method was used to s...

Outcome of interventions to improve the quality of reproductive health services provided by private health facilities in selected states in Nigeria

ABSTRACT In Nigeria, as in many developing countries, the private. health sector provides a significant proportion of reproductive health services. However, there-are concerns about the quality of the reproductive health services' provided by personnel operating in this sector. Few interventions exist to improve the quality of reproductive health services being provided by 'private practitioners', 'This three year intervention project, which was implemented in Oyo, Ogun and Gombe States, was ...

Breast cancer knowledge and screening practices among women in selected rural communities of Nigeria

ABSTRACT Globally, the devastation that befalls women diagnosed of breast cancer remains inestimable. Early detection remains a major effective approach that should be employed to combat the disease. The issue of concern, however, is whether women in the rural underserved areas are aware of these early detection methods. This study was designed to assess rural women’s awareness and knowledge of breast cancer and their screening practices. The study was a descriptive cross-sectional study ut...

Premorbid Functioning in Schizophrenia: A Controlled Study of Nigerian Patients

ABSTRACT We compared the premorbid social adjustment of 38 schizophrenic patients with that of 20 manic patients. Even though the small sample size affected the number of significant differences obtained, schizophrenic patients consistently showed evidence of poorer premorbid functioning than manics at various stages of social development. Schizophrenic men also tended to have functioned more poorly than women. Poor premorbid functioning was associated with negative syndrome, but not with pos...

Visual outcome of pressurised bottled drinks related eye injuries in Ibadan

ABSTRACT Records of 15 patients presenting with pressurised bottled drinks related eye injuries between January 1996 and 2001 were reviewed to identify factors contributing to accidental eye injuries from pressurised bottled drinks, reason for poor outcome and to make recommendations. In all, 16 eyes of 15 patients were studied out of which 7 were males (M:F, ratio I:1.1). Age range, 3 years-49 years, mean 23.6 years. The majority of those affected were students 46.7%, and traders 26.7%. The ...

Evaluation of Heavy Metal Status of Water and Soil at Ikogosi Warm Spring, Ondo State Nigeria

ABSTRACT The concentration levels of selected heavy metals, (Cu, Cd, Zn, As and Cr) were determined in the soil (µg/g) and water (ppm) samples collected at Ikogosi Warm Spring, Ekiti State, Nigeria. After digestion, Atomic Absorption Spectrophotometer (AAS) was employed for the determination. The study area was at Latitude of 7o 35' 38.9'' , Longitude of 4o 58' 52.6'' and at average elevation of 479m above mean sea level (msl). The average concentrations (µg/g) of the heavy metals in the so...

Correlation of Cag-A serologic status with histological parameters of chronic gastritis among dyspeptic patients in south western Nigeria

ABSTRACT BACKGROUND: The aim of this study was to determine the sero-prevalence of Cag-A strains of Helicobacter pylori in both dyspeptic and nondyspeptic individuals and also correlate the serological status of Cag-A strain of H. pylori with the various graded histological variables of chronic gastritis in the dyspeptic patients. 

Dyslipidemia in ART-Naive HIV-Infected Persons in Nigeria—Implications for Care

Abstract Aims: This study aimed to describe the prevalence and pattern of lipid abnormalities among antiretroviral therapy (ART)- naive HIV patients, understand if there is any relationship to virologic and immunologic status, and discuss the implications for care. Methods: This was a cross-sectional study in which baseline demographic, clinical, and laboratory data of all ART-naive HIV-infected individuals recruited into the adult ARV clinic, University College Hospital, Ibadan, between Janu...

A Survey of Antimalarial Drug Use Practices among Urban Dwellers in Abeokuta, Nigeria

ABSTRACT Drug-use pattern of anti-malarial has been associated with development of resistant strain and therapeutic failure. This descriptive cross-sectional study was carried out to assess anti-malarial drug-use practices among dwellers of Adigbe communities within Abeokuta environment. The study documented the knowledge, the attitude and behaviour of three hundred and fifty (350) respondents in terms of drug preference, attitude to drug use and the effects of non-compliance to antimalarial...

Laboratory Profile of HIV-2 and Dual HIV-1/HIV-2 Associated Acquired Immunodeficiency Syndrome in Nigeria

ABSTRACT Background: HIV-2 is comparatively less pathogenic with slow progression of infection to clinical disease and consequently there is less of information on the occurrence of HIV-2 associated disease than HIV-1. We hereby describe some laboratory profiles of individuals presenting with HIV-2 and dual HIV-1/2 related AIDS at the University College hospital in Ibadan over a period of seven years. Methodology: Blood samples from patients presenting with the AIDS defining illness at the U...

Baseline chest radiographic features among antiretroviral therapy naive human immuno-deficiency virus positive children in a pediatric care program

ABSTRACT Background: Pulmonary diseases are commonly seen in children with HIV infection, and their etioiogy is often' unclear. The-radioloqical appearances of these conditions are often non-specific. Conventional radiographs play an important role in the management of chest conditions especially in resource poor settings. Objective: This retrospective study was carried out to determine the chest radiographic pattern in children with HIV infection. Materials and Methods: The baseline chest X-...

Congenital poikiloderma with unusual hypopigmentation and acral blistering at birth

Abstract Congenital poikiloderma is an uncommon hereditary disorder. It has been reported in association with various syndromes. , No case has previously been reported from this environment. We report a case of congenital poikiloderma in a two and a half year old female Nigerian associated with unusual generalised hypopigmentation and acral blisters at birth. The child! subsequently developed macular hyperpigmentation on an erythematous background and atrophy of the skin. Although she had . ...

Screening for Retinopathy of Prematurity in Ibadan

ABSTRACT Between January to June 1995, a prospective study was carried out to determine the incidence and severity of retinopathy of prematurity (ROP) in newborn infants of less than 1,500g birthweight or less than 31 weeks gestational age. 18 babies were eligible for inclusion in this study and only one developed ROP, a Stage 1, Zone III disease i.e. 5.5% of babies at risk. In spite of the low incidence compared with other studies', it is advisable to continue the collaboration between optha...


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