The goal of this research was the discovery of newer anti-inflammatory drug. Four hydrazones with p-nitrophenyl moiety were synthesized by solvent-free and conventional synthetic methods with good to excellent yields. The synthesized hydrazones were evaluated for their anti-inflammatory activities using carrageenan-induced paw edema in mice. All the compounds indicated significant anti-inflammatory activity, demonstrating slow onset of action and longer duration of action compared to celecoxi...
The preliminary screening of phytochemical constituents of extracts of Xylopia aethiopica was evaluated. The n-hexane extract revealedthe presence of terpenoids, alkaloids, and steroids, while the presence of alkaloids, terpenoids, saponins, steroids, and phenolics was indicated in ethyl acetate extract, and the methanol extract contained tannins, flavonoids, phenolics, terpenoids, saponins, alkaloids, steroids. The medicinal property of the extracts was investigated using in-vitro antimicrob...
We designed novel p-nitrophenyl hydrazones as multi-target inhibitors of COX-2, 5-LOX, and H+/K+ ATPase in a bid to overcome side effects associated to NSAIDs and coxibs. Specifically, compounds 1-(4-nitrophenyl)-2-[(3,4,5-trimethoxyphenyl)methylidene] hydrazine (3), 4-hydroxy-2-methyl-6-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]thiochroman-1,1-dioxide (6), 4-methoxy-2-methyl-6-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]thiochroman-1,1-dioxide (8), 2-methyl-6-[(2-(4-nitrophenyl)hydraz-1-ylid...
Most commercial database systems do (or should) exploit many sorting techniques that are publicly known, but not readily available in the research literature. These techniques improve both sort performance on mod- ern computer systems and the ability to adapt gracefully to resource fluctuations in multiuser operations. This survey collects many of these techniques for easy reference by students, researchers, and product de- velopers. It covers in-memory sorting, disk-based external sorting, a...
The pyridyl based Schiff base ligands from 2-aminopyridine and benzaldehyde and 2-aminopyridine and 2, 4-dihydroxylbenzaldehyde were synthesized by: 1. For Schiff base from 2-aminopyridine and benzaldehyde; Distillation of Benzaldeyde to ensure maximum purity from possible contaminant like water and ammonia, and refluxed with freshly prepared 2-aminopyridine. The refluxing was done with ethanoic acid catalyst at a time and without catalyst. The process was followed up with Thin Layer Chromato...
This model will change the entire offline examination system as we developing a fully automated system using NLP.
Abstract “Unless and until our society recognizes cyber bullying for what it is, the suffering of thousands of silent victims will continue.” ~ Anna Maria Chavez. There had been series of research on cyber bullying which are unable to provide reliable solution to cyber bullying. In this research work, we were able to provide a permanent solution to this by developing a model capable of detecting and intercepting bullying incoming and outgoing messages with 92% accuracy. We also developed ...
Abstract Ever since the era of internet had ushered in cloud computing, there had been increase in the demand for the unlimited data available through cloud computing for data analysis, pattern recognition and technology advancement. With this also bring the problem of scalability, efficiency and security threat. This research paper focuses on how data can be dynamically mine in real time for pattern detection in a secure cloud computing environment using combination of decision tree algorith...
Abstract: Algae Play vital role in aquatic ecosystems by forming the energy base of the food web for all aquatic organisms. Thepresent study with relation to Potential of Cyanophyceae, Chlorophyceae, Bacillariophyceae, Euglenineae, classes of algae carried out for Nakane Lake of Dhule district. In Maharashtra very few workers have paid attention on limnological aspects of algae from lotic & lentic water habitat. These studies of Nakane Lake were carried out during December�...
This publication seeks to identify key factors that would make remote working in Nigeria conducive for citizens that want to practice this culture. It was discovered that power supply, a stable internet connection, digital skills and organizations adhering to remote work trends are the key factors that can make remote working pleasurable. It was also discovered that remote work improves productivity and reduces overhead costs for organizations.
The project deals with automating different task of HR department. These tasks include: On-Boarding process , Off-Boarding process , Payroll cycle. Thus, allowing the members of the department to focus on more strategic initiatives for the betterment and growth of the organization. The technologies that are used in the project are: UI-Path Studio ,Orange HRM , Microsoft Excel , Microsoft Word . AbstractRPA(Robotic process automation) is software bot that automate processes ...
ABSTRACT Digital Technologies which include Cloud Computing and Mobile Applications have emerged as catalystsforrapideconomicgrowthandcitizenempowermentacrosstheglobe.Digitaltechnologies are being increasingly used by us in everyday lives from retail stores to government offices.Theyhelpustoconnectwitheachotherandalsotoshareinformationonissuesandconcerns faced by us. In some cases they also enable resolution of those issues in near real time. Digital Locker is one of the ambitious aspect...
Social networking sites engage millions of users around the world. The users' interactions with these social sites, such as Twitter and Facebook have a tremendous impact and occasionally undesirable repercussions for daily life. The prominent social networking sites have turned into a target platform for the spammers to disperse a huge amount of irrelevant and deleterious information. Twitter, for example, has become one of the most extravagantly used platforms of all times and therefore allo...
Abstract Nowadays, big data plays a critical role in society. Big data is massive with high growth rate which is of great significance for oil and gas companies, however, a large amount of data often brings a lot of storage and management costs, such as the cost of hard disks. Here is where our application makes sense. Hence the researchers developed an application for HyperDap Ltd that filters data according to some criteria before writing into the database in order to save storage space and...
Tuberculosis is a type of chronic diseases, thus needs long term treatment. Each year, over 2 lakh people in India are affected by TB and on average around 20,000 people are infected every month in each state. According to WHO, primary statistics collated from 84 countries, approximately less than 1.4 million persons received tuberculosis (TB) treatment in 2020 than in 2019, (i.e. 21% decline from 2019). An early detection can significantly shorten the treatment period. In this study, we’ve...