AbstractNanotechnology is the study and application of extremely minute structures known as nanomaterials. These nanomaterials have sizes ranging from 0.1-100nm. Nanomaterials are produced using two approaches which are the bottom up approach and the top down approach and have been applied to various fields including medicine. The application of nanotechnology in medicine is known as nanomedicine. Nanomaterials such as liposomes, dendrimers, and quantum dots have been applied in disease diagn...
INTRODUCTION Oxygen is an indispensable element for life. Oxidative property of oxygen plays a vital role in various biological phenomena; being essential for life, oxygen can also aggravate the damage within the cell by oxidative events. Oxygen is used by the cell to generate energy and free radicals are formed as a consequence of ATP (adenosine triphosphate) production by the mitochondria. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are the by-products resulting from t...
Cellulose is the most abundant, structural, biological organic compound on Earth which is widely used in paper and textile industries. In this project work, the blend of compressive character of Urea-Formaldehyde Resin with addition of Cellulose is tested. Cellulose can be extracted from dried plant by alkaline treatment (mercerization), followed by neutralization with acid; product of which undergoes bleaching to produce pure form of cellulose. Urea Formaldehyde Resin c...
Psychrophilic enzymes are biocatalysts that control biochemical processes at low temperatures by either accelerating or decreasing the reaction rate. These enzymes are mainly obtained from microorganisms which inhabit cold environments and proliferate at low temperatures. The cold-loving organisms referred to as psychrophiles are adapted to the extreme cold conditions which resulted in changes in their biochemical machineries such as their enzymes. This resulted in certain characteristics of ...
ABSTRACT The neuromuscular junction (NMJ) is a unique, specialized chemical synapse that plays a crucial role in transmitting and amplifying information from spinal motor neurons to skeletal muscles. NMJ complexity ensures closely intertwined interactions between numerous synaptic vesicles, signaling molecules, ion channels, motor neurons, glia, and muscle fibers, making it difficult to dissect the underlying mechanisms and factors affecting neuro-degeneration and muscle loss. Muscle fiber...
ABSTRACT Ivermectin (IVM), a dihydro derivative of avermectin (AVM), originating solely from the fermentation products of Streptomyces avermitilis had an immeasurably beneficial impact in improving the lives and welfare of billions of people worldwide. Originally introduced as a veterinary drug, it was quickly discovered to be ideal in combating two of the world’s most devastating and disfiguring diseases; onchocerciasis and lymphatic filariasis (LF) which has plagued the world’s poor ...
ABSTRACT Tungiasis is an ecto-parasitic disease of humans and animals caused by the burrowing of gravid female fleas of the genus ‘Tunga’. Of the known species of Tunga fleas, Tunga penetrans and Tunga trimamillata are parasites of humans besides other warm blooded mammals, most of which are peri-domestic. The host of the others is limited to a few genera of wild mammals. The burrowed female flea rapidly expands its body size, causing immense itching, inflammation, pain and debilitation. ...
verviewStatsCommentsCitationsReferences (29)Related research (10+) AbstractEnvironmental investigations show that the Archaea are diverse and abundant not only in extreme environments, but also in soil, oceans and freshwater, where they may exhbit a key function in the biogeochemical cycles of the planet. Archaea display unique capacities, such as methanogenesis and survival at temperatures higher than 90 °C that make them crucial for understanding the nature of the biota of early Earth. M...
Fungi are ubiquitous plant pathogens that are major spoilage agents of foods and feedstuffs. The infection of plants by various fungi not only results in reduction in crop yield and quality with significant economic losses but also contamination of grains with poisonous fungal secondary metabolites called mycotoxins. There is an urgent need to address the food safety and International trade issues associated with mycotoxin contamination in Nigerian consumer goods and agricultural products be...
Food poisoning is a term applied to an acute intestinal disease acquired by the consumption of food or drinks (e.g. juice, water, wine). The toxic agents responsible for food poisoning include the following; microorganisms that occur naturally in humans, animals and/or the environment, naturally occurring toxins that occur in food naturally or produce toxins inside the food through normal biological processes. Food poisoning is often confused with food allergy and food adverse effects, which ...
Street food vending is a common feature of most cities and towns in developing countries, Aside provision of ready-made instant meals at relatively inexpensive prices, teeming urban dwellers are attached to street foods because of its gustatory attributes. Street food vending makes up the significant proportion of informal sector of the economy of most developing countries. Street foods contribute to a significant number of food poisonings due to paucity of data deficiencies in knowledge abou...
The rise in the tide of information technology has led to an increase in the large amount of personal information that could be collected from an individual, thus breaching personal privacy. Protecting the individual personal information is paramount as it bothers on the dignity of the consumer and his right to solitude. While the Constitution of Nigeria provides for the protection of dignity of the Nigerian in section 37 and section 34 for protection of privacy sectoral laws are also in...
Executive decision support system is a system that is intended to be used by senior managers directly to provide assistance with decision making in their management activities through decision support system in industries. Examples of these intelligent information which is often the source of executive decision support system are External databases, Technology reports like patent records etc., Technical reports from consultants, Market reports, Confidential information about competitors, Spec...
ABSTRACT In a bid to determine the groundwater potential of some parts Orsu and environs, which lies within latitude N5º53.858΄ to N5º47.572΄ and longitude E7º0.847΄ to E6º56.988΄, a total of ten (10) vertical electrical soundings were carried out. The study area belongs to the Anambra basin which is one of Nigeria’s most important hydrological basins. It is overlain by the Miocene to recent Benin formation and Eocene Ameki formation.Equipment such as ABEM terrameter SA...
ABSTRACT Schistosomiasis is a water-borne parasitic disease caused by schistosomes and transmitted by fully aquatic or amphibious freshwater snails in whose bodies the human-infective larvae, cercariae, develop. Adult schistosome worms colonise human blood vessels for years, successfully evading the immune system while excreting hundreds to thousands of eggs daily, which must either leave the body in excreta and/or urine or become trapped in nearby tissues. Trapped eggs induce a dist...