ABSTRACT Nimesulide microspheres were prepared by the quasi-emulsion solvent diffusion method, using acetylated starches of the indigenous Ofada rice (Oryza glaberrima Steud) with degrees of substitution (DS) 1.42 and 2.62. A full 23 factorial experimental design was performed using DS (X1), drug:polymer ratio (X2) and polymer concentration (X3) as independent factors; size, entrapment, swelling and time taken for 80% drug release (t80) were the dependent variables. Contour plots were generat...
ABSTRACT Stress levels and affective states in children aged between 11-14 years are impacted by developmental tasks, peer interaction, peer acceptance and psychosocial adjustment. In addition to this, slower development of regulatory systems and rapid arousal and motivation development increases stress levels and affective states of adolescents leading to internalization and/or externalization (maladaptive anger). This study focuses on the experience of and the risk factors associated with ...
Abstract Background: The incidence of HIV infection and AIDS is rising in Nigeria. Surgeons are at risk of occupationally acquired infection as a result of intimate contact with the blood and body fluids of patients. This study set out to determine the knowledge, attitude and risk perception of Nigerian surgery residents to HIV infection and AIDS. Methods: A self-administered postal questionnaire was sent to all surgery trainees in Nigeria in 1997. Results: Parenteral exposure to patients' bl...
ABSTRACT Namibia, one of the countries hardest hit by HIV/AIDS, has embarked on a large scale public health sector roll-out of ART. The Catholic Health Services is implementing an HIV/AIDS treatment program in the Andara district since 2004. Even though there is strong evidence to show that antiretroviral therapy (ART) improves the survival and quality of life of people living with HIV/AIDS (PLWHA), an increased trend of mortality in patients on ART in the Andara district was observed, but t...
ABSTRACT The Ministry of Health and Social Services in Namibia has embarked on a fight against the human immunodeficiency virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) pandemic. The human immunodeficiency virus counselling and testing (HCT) services comprises the core component of the prevention, treatment and care pertaining to HIV. The purpose of this study was to investigate the effect of the renovation of health facilities on the HCT service utilisation. The study used a quantitati...
ABSTRACT There is increasing evidence that major depression impacts the course of HIV infection, yet few studies have explored demographic and clinical predictors of depression in people who with HIV/AIDS. This study investigated predictors of depression (e.g., demographic and clinical variables, negative life events, and coping response) among outpatients with recently diagnosed HIV/AIDS patients in South Africa. One hundred forty-nine recently diagnosed HIV/AIDS patients (44 males and 105 f...
ABSTRACT Violence against women is embedded in most cultures with pregnancy associated with higher rates. This study assessed the pattern of violence in pregnancy in two maternity centres in Ibadan, Nigeria. This was a cross-sectional study of antenatal clinic attendees, between 1 and 31 March, 2007 at the University College Hospital (UCH) and the Adeoyo Maternity (AMH). By systematic random sampling, 404 women were interviewed. Analysis was done by means, w2-test (at 5% level of significa...
ABSTRACT SUMMARY Aim: In .ctrospectivclv assess the outcome of trabecu lectcmv performed using an intraoperative sponge soaked 5-fluorouracil (50 mg/ ml). Methods: Trabeculcctornv with an intraoperative sponge soaked with 5-f1uorouracil (5-fU) was performed in 21 eyes of 1-+ patients. The reduction in in traocular press ure (lOP), com plications and va ria tions in visual acuity were noted. Results: The mean preoperative lOP was 31.5 ± 10.6 mmHg. The mean postoperative lOP was 7.3 ± 5.7m...
ABSTRACT This study was designed to assess the knowledge, attitude and adoption of appropriate infant feeding practices of mothers and the anthropometric indices of their children. Three hundred and seventy three mothers who attended infant welfare clinics at the three health settings (General hospital Ekwulobia, Primary health care Ekwulobia, and Primary health care Akpo) all in Aguata L.G.A were involved in the study. The study evaluated the nutritional status of the infants in relation to...
ABSTRACT This epidemiological study was to elicit information on the consumption pattern of antioxidant-rich foods among middle-aged adults in Enugu North local government area, Enugu State, Nigeria. Four hundred adult men and women aged 40-60 years were used for the study. Multiple- staged stratified random sampling technique was used for the selection of the subjects used for the study. The respondents were randomly selected from 10 streets in the 5 urban zones making up the Enugu North l...
ABSTRACT Reports show that most maternal deaths occur during the post natal period, yet this is when coverage and programmes of maternal and child health are at their lowest along the continuum of care in the local government, state, country and African region at large. Therefore it is important to investigate postnatal care practices carried out by mothers to reduce the trend. The aim of this is study was to assess postnatal care practices with respect to, perineal wound care, breast-feedin...
Abstract Fifty (50) Non-diabetic Hypertensive Patients in the medical out-patient (MOP) department of University of Nigeria Teaching Hospital (UNTH), Ituku Ozalla, Enugu, Nigeria aged 40-78 years comprising 25 males and 25 females were investigated. Also fifty age and sex-matched apparently healthy subjects served as the control group. The following variables were determined using standard methods: prothrombin Time, Activated partial Thromboplastin Time, Fibrinogen Assay, platelet Count, Fas...
ABSTRACT The study was carried out using randomized 121 in-patient diabetics in medical wards of University of Nigeria Teaching Hospital (UNTH) Ituku-Ozalla. The instrument for data collection was structured, validated pre-tested questionnaires, anthropometry and dietary study. Body mass index was calculated for each patient using weight and height measurements. The adequacy of nutrient intake was assessed by comparing the energy and nutrient intakes of patient with FAO/WHO requirements. The...
ABSTRACT Leaf of Vernonia amygdalina has been shown to have hypoglycemic activity. This may be as a result of the presence of secondary metabolites as its constituents. The major secondary metabolites present in the leaf are tannins, carbohydrates, reducing sugars, glycosides, steroids and proteins. This work was designed to identify these secondary metabolites responsible for this activity, test the lethality of the constituents and then determine the best solvent for extraction. A 1 kg cru...
ABSTRACT Landolphia owariensis P. Beauv (Apocynaceae) is a woody liane commonly used in Africa for the treatment of gonorrhea, worm infestation and malaria. The methanol leaf extract (ME) of L. owariensis was obtained by cold maceration and then fractionated into nhexane (nHF), ethylacetate (EF) and methanol (MF) fractions. The methanol extract and fractions were tested against chloroquine-sensitive Plasmodium berghei berghei in early, established and repository models of infection using Pe...