Medical & Health Sciences

Research Papers/Topics in Medical & Health Sciences

How do Composite (CAD/CAM) crowns compare to ceramic crowns in terms of clinical restoration survival? [November 26, 2017]

Search result: One clinical trial was found.Clinical outcomes: The results suggest that Composite (CAD/CAM) crowns are inferior to ceramic crowns after 3 years.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do no...

How do Fibre posts compare to Metal posts in terms of clinical restoration survival? [November 25, 2017]

Search result: Two systematic reviews and two additional trial reports that were not covered by the systematic reviews were found.Clinical outcomes: The older systematic review (2005) included only one relevant trial not included in the other more recent systematic review (2014) and stated higher failure risk for metal-posts. However, the more recent systematic review included 14 trials and found no significant differences. In addition, one trial indicated higher fracture risk ...

How do 2-step etching systems compare to 3-step etching systems in terms of clinical restoration survival? [November 20, 2017]

Search result: Two systematic reviews and one additional trial reports were found.Clinical outcomes: While the trial report and one systematic review indicated no significant difference, one other systematic review suggests 3-step systems to be superior to 2-step systems for composite restorations in cervical cavities and inferior for composite restorations in load-bearing cavities of permanent teeth.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic ...

How do 1-step etching systems compare to 3-step etching systems in terms of clinical restoration survival? [November 18, 2017]

Search result: Two systematic reviews and one additional trial report were found.Clinical outcomes: While the trial report indicated no significant difference, one systematic review provided no data while the other indicated that 3-step self-etching systems to be superior to 1-step self-etching systems (no information were provided for 3-step versus 1-step etch-and-rinse systems).[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches o...

How do 1-step etching systems compare to 2-step etching systems in terms of clinical restoration survival? [November 17, 2017]

Search result: Two systematic reviews and 5 additional trial reports were found.Clinical outcomes: While the trial reports indicate no significant difference, the systematic reviews suggest 2-step systems to be superior to 1-step systems.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as ...

How do HEMA free bonding agents compare to HEMA containing bonding agents in terms of clinical restoration survival? [November 16, 2017]

Search result: Three studies were found.Clinical outcomes: The result indicates no differences between HEMA containing and HEMA-free bonding agents for most clinical outcomes after 3 and 5 years. In addition, restorations with HEMA-free agents appear to have some higher dentin retention after 5 years, while exhibiting more incisal marginal defects and discolorations after 3 years.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches o...

Clinical effect of MTA cement for pulp capping [November 14, 2017]

Search result: 2 systematic reviews and 9 clinical trials were found.Clinical outcomes: The results suggest MTA to be effective for pulp capping.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the n...

Clinical merits of restorative treatment of root (cervical) caries lesions [November 13, 2017]

Search result: 7 trials were found.Clinical outcomes: The results suggest that various composites (nanohybrid, flowable) show good results. Etch-and-rinse adhesives appear to be superior to all-in-one adhesives, while compomers and resin-modified glass-ionomers appear to be less effective than composites.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinic...

What is the clinical longevity of lithium disilicate ceramics? [November 24, 2017]

Search result: 5 trials and 6 systematic reviews were found. .Clinical outcomes: The results suggest that:(i) for lithium disilicate single crowns, the existing evidence indicates excellent short-term survival rates, but the evidence for medium-term survival is limited;(ii) for lithium disilicate fixed dental prostheses, the evidence for short-term survival is fair, although limited, but the evidence for medium-term survival is not promising;(iii) there is contradicting evidence whe...

Have stannous ions any remineralising effect on dental tissues? (Therapeutic) [November 11, 2017]

Search result: 11 trials were found.Clinical outcomes: The results suggest that stannous ions may have a caries/demineralisation preventive effect (particularly when stannous fluoride was compared to sodium fluoride).[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessmen...

Have stannous ions any remineralising effect on dental tissues? (Therapeutic) [November 10, 2017]

Search result: 5 trials were found.Clinical outcomes: The results of the laboratory trials appear contradictory particularly when stannous fluoride was compared to sodium fluoride).[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity...

Have stannous ions any antibiotic effect on oral bacteria? [November 9, 2017]

Search result: 9 trials were found.Clinical outcomes: The results of the mainly laboratory trials suggest that stannous ions have an inhibiting effect on oral bacteria (particularly when stannous fluoride was compared to sodium fluoride).[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as ...

Has zinc any antibiotic effect on oral bacteria? [November 8, 2017]

Search result: 13 trials were found.Clinical outcomes: The results of the mainly laboratory trials suggest that zinc has an inhibiting effect on oral bacteria.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not...

What are the clinical merits of chemically cured glassionomers (GIC) for placing cervical tooth restorations? [November 07, 2017]

Search result: Only trials with low-viscosity GIC were found.Clinical outcomes: The results suggest that cervical restorations placed with chemically cured GICs have good survival rates when compared to composite but are less aesthetic.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as we...

Potential of adverse effects due to aluminium, barium and strontium in GIC [November 06, 2017]

Search result: No clinical evidence concerning adverse effects of aluminium, barium or strontium released from GICs were found.Clinical outcomes: A review of the relevant laboratory literature, including a conservative calculation of any potential adverse clinical effect due to aluminium content, concludes that the amount of aluminum that could be leached into the body from glass-ionomer dental fillings is well below the permitted daily dose and almost certainly too small to ha...


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