Medical & Health Sciences

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Medical & Health Sciences Research Papers/Topics

Etch-rinse systems with and without selective enamel etching [November 02, 2015]

Search result: Three clinical trials were found. Clinical outcomes: The results indicate that additional selective enamel etching does not improve the clinical performance of restorations. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictory and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results. [‘Preliminary Systematic Literature Searches’ are ba...

Selective enamel etching effect on clinical performance of selfetch / self-adhesive systems [November 02, 2015]

Search result: Eleven clinical trials were found. Clinical outcomes: Minor or no improvements are reported when selective enamel etching was used. Selective enamel etching may not pose a hazard in terms of postoperative hypersensitivity. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictive and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results. [‘Prel...

Advantages of Self-etch versus Etch-and-rinse systems [October 28, 2015]

Search result: Eight articles reporting on 4 clinical trials after different follow-up periods were found. Clinical outcomes: The results indicate no difference in retention and anatomic form of restorations after 1 – 3 years. Marginal adaptation appears to be superior for etch-and-rinse systems after 1 – 2 years and no difference was found after 3 years. Marginal discoloration is significantly more observed for (1-step) self-etch systems. Post-operative sensitivity was the same for bo...

Resin infiltration to stop carious lesion progression [October 28, 2015]

Search result: Eight clinical studies were found. Clinical outcomes: The results suggest efficacy of resin-infiltration technique to stop caries progression and to improve aesthetic appearance of white spot lesions (WSL). However, discomfort levels appear to be higher than with other noninvasive interventions. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s peri...

Anticaries effect of CPP-ACP [October 23, 2015]

Search result: 21 clinical studies were found. In-situ studies, as well as studies including ACP/casein materials not covered by the Recaldent technology were not included. Clinical outcomes: The results regarding the clinical efficacy of CPP-ACP in the prevention and treatment of dental caries, i.e. slowing the progress of early caries lesions/white spot lesions appears to be contradictive and no conclusive statement can yet be made based on the available evidence. State of evidence and r...

GIC versus RM-GIC as fissure sealant [October 20, 2015]

Search result: Only one clinical study was found. Clinical outcomes: The results indicate no difference in the caries preventive effect between both materials as fissure sealants in permanent teeth. The retention rate of RM-GIC in pits and fissures was higher than for conventional GIC. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches o...

Fluoride release of resin-modified GIC versus fluoride containing composite resin [October 20, 2015]

Search result: Only two clinical studies were found. Clinical outcomes: The results indicate that GICs release more fluoride under clinical conditions than fluoride containing composite resin. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are l...

Fluoride release of resin-modified GIC versus Compomers [October 16, 2015]

Search result: Two clinical studies were found. Clinical outcomes: The results indicate a higher fluoride concentration in plaque surrounding teeth that were either bonded or restored with resin-modified GIC than with compomer. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over e...

Longevity of conventional GIC versus compomers in primary teeth [October 16, 2015]

Search result: Four clinical studies concerning restorations were found.. Clinical outcomes: The results indicate no difference in the success rate between both types of material if high-viscosity GIC was compared against Compomers. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews o...

Survival rate of ART restorations with high-viscosity GIC versus conventional RM-GIC [October 12, 2015]

Search result: Only two clinical studies concerning restorations were found. Clinical outcomes: The results indicate no difference in the survival rate after 12 and 24 months. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the numb...

Retention of conventional GIC versus RM-GIC restorations [October 11, 2015]

Search result: There is still a lack of studies to this topic and only two clinical studies concerning restorations were found. Clinical outcomes: The results indicate no difference in the retention rate after 12 and 42 months in Class V and Class II restorations, respectively. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the d...

The current evidence for caries prevention and treatment in xeriostomic patients [October 11, 2015]

Search result: Ten controlled clinical studies relevant to the topic were found. Clinical outcomes: The results indicate: - GIC/RM-GIC have higher caries-preventive effects than composite/amalgam in cases were no additional fluoride was provided to patients have been shown; - Topical fluoride is indicated as caries-preventive; - Mineral containing supplements, with and without casein appear to be at least as effective as topical fluoride in caries prevention; - The effect of chlorhexidine ge...

Retention of GIC versus Amalgam as restorations [October 06, 2015]

Search result: There is still a lack of studies to this topic and only two clinical studies concerning restorations in the primary dentition were found. Clinical outcomes: The results of (conventional) high-viscosity GIC indicate no difference to amalgam while, lowviscosity GIC perform significantly worse than amalgam. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM...

Longevity of resin-modified GIC versus compomers in primary teeth [October 06, 2015]

Search result: Only three clinical studies were found. Clinical outcomes: The results indicate no difference in the longevity between both types of materials. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases ...

The Systematic Review initiative for Evidence-based Minimum Intervention in Dentistry (SYSTEM): activities 2015/16

In 2012, the Systematic Review initiative for Evidence-based Minimum Intervention in Dentistry (SYSTEM) has been accepted as research entity with programme status within the Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa. The aim of the initiative is to establish an applicable evidence-based body of clinical knowledge in the field of Minimum Intervention (MI) dentistry. This article provides a brief overview over SYSTEM’s activities during 2015/16.


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