ABSTRACT Diabetes Mellitus Foot Syndrome (DMFS) occurs against a background infection, neuropathy and peripheral arterial disease (PAD). Clinical assessment often under diagnoses PAD. However, the use of a hand held Doppler 10 calculate the ankle brachial index (ABI) is an inexpensive, non- invasive and quantitative method of determining the presence of PAD. A retrospective analysis of patients with DMFS who had PAD assessment with a hand held Doppler was done. Data retrieved from the doppler...
Objective: To determine the perinatal mortality rate in Lagos University Teaching Hospital at the close of the 20th century. Materials and Methods: Routinely collected data from the Departments of Obstetrics & Gynaecology and Paediatrics from January 1996 to December 2000, were analysed. The data included total deliveries, stillbirths and early neonatal deaths. Results: A total of 6,759 deliveries, including 163 multiple pregnancies, occurred during the period. There were 573 perinatal deaths...
Abstract Background: There has been a marked increase in people with disability all over the world including Tanzania. Consequently, the psychiatric disabled people are not healthily maintained, become apathetic, have difficult in trouble coping, are discriminated against, are not integrated into local communities, and most of them face massive unemployment. To address this condition of psychiatric disability, the Tanzanian government established Mirembe psychiatric hospital and Hombolo reh...
Abstract Background: Sickle cell anaemia (SCA) is associated with growth failure. However, recent reports indicate high rates of overweight or obesity among children with SCA in developed countries. It is unclear whether overweight or obesity is also common in children with SCA in developing countries. The objectives of the study were to determine the prevalence of overweight or obesity, wasting and stunting and identify predictors of wasting and stunting among children with SCA in Nigeria. ...
Abstract Introduction: irritable bowel syndrome (IBS) is one of the functional gastrointestinal disorders (FGIDs) which has been well described in western populations especially as the commonest cause of recurrent abdominal pain The aim of this study was to document the prevalence of Irritable bowel syndrome (IBS) amongst children in western Nigeria and increase the aware ness of IBS amongst physicians who manage children with abdominal pain. Methods: This was a cross-sectional study conduc...
SUMMARY Objectives: To review the prevalence and pattern of cardiovascular disorders in childhood autopsies in Lagos University Teaching Hospital (LUTH). To also determine the frequency of associated extra cardiac complications and characteristics of children with cardiovascular diseases that died. Materials and Methods: The autopsy register of the department of Morbid anatomy for the years 1991 to 2000 in LUTH was retrospectively reviewed. Data extracted including age, sex, primary diagnos...
Abstract Introduction: Children with steroid resistant nephrotic syndrome usually require treatment with second-line agents and calcineurin inhibitors such as cyclosporine are now recommended as initial therapy. These agents only recently become available in our environment and their impact on care is unknown. We reviewed the short-term treatment outcomes of their use in comparison with previous outcomes. Methods: Medical records of children managed for idiopathic steroid resistant nephroti...
Abstract Respiratory distress syndrome (RDS) is a common health problem especially in preterm newborns. In Nigeria, prematurity accounts for about 25% of neonatal mortality and RDS have been identified as the major cause of these deaths. The major problem in RDS is immaturity of the lungs with deficiency of surfactant. Surfactant reduces surface tension in the alveoli, thereby preventing collapse of the lungs during expiration. Bubble continuous positive airway pressure (bCPAP) is a low cost...
Abstract Background: Vaccine preventable diseases still account for a large proportion of childhood morbidity and mortality in children less than five of age. The decline in immunization coverage over the years has worsened this resulting in the re-emergence of hitherto controlled infections such as diphtheria. Objective: To review the presentation, management and outcome of cases of probable diphtheria seen at the children emergency centre at the Lagos University Teaching Hospital. Metho...
ABSTRACT Background: Retinoblastoma is the most common intraocular childhood malignancy. Its management is, however, not without challenges especially in a developing country like Nigeria. This study sought to present the clinical profile and treatment outcome of patients with retinoblastoma managed in a Nigerian tertiary eye care facility highlighting the challenges with a view to improving the management of the disease. Materials and Methods: Aretrospective, single-institution, and institu...
Abstract The prevalence of diverse factors affecting maintenance management determines the impact of such factors on the maintenance of prison facilities. This study investigates factors that affect the maintenance management of prison facilities in South-West, Nigeria. Questionnaires were used to collect data from the prison staff in the maintenance unit of all prisons situated in South-west, Nigeria. The statistical tools employed for the study were percentage, mean scores, kendall's coeff...
ABSTRACT Moringa oleifera is the most widespread species of the genus Moringa, the only genus in the family Moringaceae. It is a very popular plant used in traditional herbal medicine. Different parts of the plant contain a profile of important minerals and phytochemicals. The leaves and seeds are good sources of proteins, vitamins, beta-carotene, amino acids, and phenolic compounds. Study was carried out to check chemical constituents of leaves and seed oil of M. oleifera obtained from Ikor...
ABSTRACT Justification for the requests for homologous blood that accompany major elective maxillofacial surgical procedures is difficult to establish in most cases. This attitude of ordering for cross-matched blood is understandable in today's legal climate, but has led to serious problems in terms of laboratory inefficiency which can no longer be ignored. To evaluate the pattern of ordering and use of homologous blood, and transfusion ratios for major elective maxillofacial surgeries at th...
ABSTRACT 22q11.2 deletion syndrome (22q11.2 DS) is the most common microdeletion syndrome and is underdiagnosed in diverse populations. This syndrome has a variable phenotype and affects multiple systems, making early recognition imperative. In this study, individuals from diverse populations with 22q11.2 DS were evaluated clinically and by facial analysis technology. Clinical information from 106 individuals and images from 101 were collected from individuals with 22q11.2 DS from 11 countrie...
Background: Food allergy has been well described in white children, and cow’s milk protein allergy (CMPA) still remains the most common allergy in these children. Information on the same subject in developing countries is very limited, and management of this condition remains challenging. Case presentation: We report on two cases of children with multiple food allergies. The first patient presented with chronic diarrhoea following the introduction and use of several infant formulas, while ...