For a human being to be formed there must surely be a man and a woman. The man will produce sperm and the woman will produce eggs.
The present work reports a theoretical study on vibrational spectra and nonlinear optical properties of azobenzene derivatives. The theoretical geometrical parameters in the ground state have been investigated by density functional method using B3LYP functional and 6-311G++ (d, p) basis set. The analysis of calculated IR and VCD indicates that the binaphthyl and alkoxy side chain of azobenzenes derivatives contribute differently to spectral line shape. The out-of-phase bending and twisting of...
Several physiochemical, structural and quantum-mechanics based descriptors were derived for a set of anilide derivatives, using DFT-B3LYP/6-311G (d, p) level of theory. The aim of this study was to develop QSAR model using multiple linear regression to predict the antimicrobial activity of anilides towards E. Coli in terms of several electronic and molecular descriptors. The best-fit model involved electrophilicity index (w) in conjunction with molecular weight (W) and logarithm of the octano...
A method to create smart and flexible switches for the regulation of liquid flow across multiple channels is essential in paper microfluidics. Prior approaches are hampered by long response times, high actuation fluid volumes, and external control circuitry. To diminish these problems, we designed a distinctive actuator device fashioned entirely from chromatography paper and featuring folds. The fold can be selectively wetted by an actuation fluid at either the crest or trough, resulting in t...
The emergence of new drugs is often driven by the escalating resistance of parasites to existing drugs and the accessibility of more advanced technology platforms. Microfluidic devices have allowed for quicker testing of compounds, regulated sampling/sorting of entire animals, and automated behavioral pattern detection. In the majority of microfluidic devices, the effects of drugs on small animals (e.g. Caenorhabditis elegans)elegant are quantified by an endpoint, dose response curve that sho...
This new microfluidic platform offers a more sensitive method for screening drugs and their effects on the locomotion of free living and parasitic nematodes. The chip is capable of monitoring four nematode parameters (number of worms responsive, number of worms leaving the drug well, average worm velocity and time until unresponsiveness) to provide a more detailed analysis and resolution of drug resistance. The drug screening experiment is divided into three parts: pre-exposure study, dose ex...
The transmembrane proteins known as ion channels play a role in controlling and preserving the ionic concentrations across the cell membrane. Modeling the flux of ions in and out of these channels on an atomic level is essential for understanding several neurological diseases and related pharmaceutical discoveries. Recent experimental research has provided information on the channel's physical structure which can be used to create realistic ion transport models. Different trajectories exist f...
The transmembrane proteins known as ion channels play a role in controlling and preserving the ionic concentrations across the cell membrane. Modeling the flux of ions in and out of these channels on an atomic level is essential for understanding several neurological diseases and related pharmaceutical discoveries. Recent experimental research has provided information on the channel's physical structure which can be used to create realistic ion transport models. Different trajectories exist f...
This paper looks at a movement-based assay to analyze adaptability in Caenorhabditis elegans locomotion behavior. A series of sinusoidal microchannels of fixed wavelength and varying amplitude, with the width being similar to the body diameter of the organism, are used for this purpose. The worms are allowed to enter the channel from the input and transition towards the output port. In sections that are similar to the worms' undulations, the movement is fast and steady. However, as the channe...
This paper looks at a movement-based assay to analyze adaptability in Caenorhabditis elegans locomotion behavior. A series of sinusoidal microchannels of fixed wavelength and varying amplitude, with the width being similar to the body diameter of the organism, are used for this purpose. The worms are allowed to enter the channel from the input and transition towards the output port. In sections that are similar to the worms' undulations, the movement is fast and steady. However, as the channe...
An open microfluidic system has been developed to dispense and manipulate individual droplets on plastic sheets. Superhydrophobic material is applied to the surface of obtainable plastic sheets by spraying, then hydrophilic symbols are printed with an inkjet printer. The plastic sheets are connected to a two-axis tilting platform driven by stepper motors, which produces mechanical agitation enabling droplet transport. The system has been demonstrated to carry out various droplet operations, s...
Emmanuel, O. (2008). Taking risky opportunities in youthful content creation: teenagers' use of social networking sites for intimacy, privacy and self-expression. New Media & Society, 10(3), 393-411
An Introduction to Computer Science and Problem Solving
INTRODUCTION TO PROBLEM SOLVING An algorithm is a sequence of simple steps that can be followed to solve a problem. These steps must be organized in a logical, and clear manner. We design algorithms using three basic methods of control: sequence, selection, and repetition. 1.1 Sequential control. Sequential Control means that the steps of an algorithm are carried out in a sequential manner where each step is executed exactly once. Let’s look at the following problem: We need to obtain the t...
A computer is an electronic device that receives input, stores or processes the input as per user instructions and provides output in desired format. Input-Process-Output Model Computer input is called data and the output obtained after processing it, based on user’s instructions is called information.