ABSTRACT Introduction: Paracetamol (acetaminophen) is a widely used over-the-counter analgesic and antipyretic drug which is known to cause liver injuries in both humans and experimental animals when administered in overdose. Supratherapeutic dose of paracetamol results in accumulation of reactive oxygen species (ROS) which impairs the antioxidants defence mechanisms and thus, causes a redox imbalance. The resulting oxidative stress plays a vital role in paracetamol-induced hepatic toxicity....
ABSTRACT Introduction: “Ghana‘s current Maternal Mortality Ratio (MMR) of 319 per 100,000 live births makes achievement of the Sustainable Development Goal of 70 maternal deaths per 100,000 live births or less by 2030 appears to be deceptive‖ (Gudu & Addo, 2017). Even though skilled attendance during childbirth is a crucial approach to decreasing maternal mortality, the proportion of deliveries taking place within health facilities where such assistance is provided is very low in Ghana...
ABSTRACT In spite of the available modern technologies for dealing with ill-health, many people continue to resort to divination in the search for therapy. The persistence of the practice of divination in health seeking suggests that there is a considerable use derived from its practice. Against this background this study was conducted to assess the extent to which divination influences health-seeking behaviour as people utilise modern healthcare facilities in the Talensi-Nabdam district in ...
ABSTRACT Background Male involvement in maternal healthcare has become critical given that men as the heads of the family control the finances, are decision-makers and provide emotional and social support which directly influence the antenatal, delivery, and post-natal care. Male involvement can, therefore, have diverse positive effects on maternal health in the form of reduction of maternal morbidity and mortality. In Kpone Sub-Municipality where poor maternal outcomes are still recorded, i...
ABSTRACT Background: There has been a reduction in HIV and AIDS associated morbidity and mortality since the introduction of antiretroviral therapy. However, in contrast to the developed world, very little is documented about the influence of Highly Active Anti-Retroviral Therapy (HAART) on the Quality of Life of HIV patients in developing countries. In Ghana Quality of Life is rarely assessed. This highlights an important gap in the assessment of the health status of HIV and AIDS affected p...
ABSTRACT Diabetes mellitus is a metabolic disease resulting from the body’s inability to produce and utilize insulin effectively. Living with type -2 diabetes mellitus has been associated with several challenges. Identification of these challenges would help in holistic healthcare provision for persons living with type-2 diabetes mellitus. This study explored the lived experiences of persons living with type-2 diabetes mellitus in Accra by examining their psychosocial experiences as well a...
Abstract The need for effective client education is an important component in midwifery practice. The benefits include a decrease in maternal mortality and morbidity. The purpose of this study was to explore the learning needs of multigravid women. The study was qualitative in nature and an exploratory- descriptive design was adopted. Eighteen multigravid women were selected for the study through a purposive convenience sampling technique. Eight women were interviewed individually and ten en...
ABSTRACT Background: Micronutrients are extremely important components of a high-quality diet and even though they are required in very small amounts, they are important in the building of healthy brains, bones and body. Micronutrient deficiency is a problem as its effects are irreversible. In Africa, vitamin A deficiency is reported to be the cause of about 6% of deaths of children under the age of 5 years, and a major public health issue in Ghana. Inadequate dietary intake of vitamin A-ric...
ABSTRACT Sulphadoxine-Pyremethamine (SP) has been an ideal choice of drug for Intermittent Preventive Treatment (IPT) of malaria; however, due to widespread resistance of the malaria parasite to this drug, there has arisen need to find alternative anti-malarial drugs for IPT to replace it. It has been suggested that short-acting drugs are unsuitable for IPT. A longitudinal cohort study of the epidemiology of pediatric malaria was conducted in Kombewa Division, Western Kenya between 2003 and ...
ABSTRACT Men who have sex with men (MSM) suffer disproportionate burden of HIV which is often associated with stigma and discrimination. HIV stigma is believed to be associated with negative psychosocial consequences that affects treatment outcomes. This study sought to explore the psychosocial experiences of key population (MSM) living with HIV using the socio-ecological model. A qualitative interpretive descriptive -approach was employed. Snowballing sampling technique was used to select f...
ABSTRACT The Primary Health Care in Ghana which started as fa r back as 1978 is based on the three tier structure namely the District; subdistrict and community levels. The Subdistrict level is to act as a link between the District level and the Community level. However, the subdistrict level was recognised as a weak link in translating policies into significant health impact by the Ministry o f Health, (MOH). In an attempt to address these problems, subdistrict health systems were form ed ...
ABSTRACT In rural savannah areas of Nigeria, Echics ocellatus (Carpet viper) is responsible for high incidence of snakebite morbidity and mortality. The snakebites are commonly treated with plant extracts in form of traditional medicine. The antivenom activity of Paullinia pinnata Linn and Detarium microcarpum Guill and Perr, popular herbs used in the treatment of Echis ocellatus bites are of great interest and were investigated in vivo and in vitro against the venom (2mg/kg) of Echis carniat...
ABSTRACT Background: Malaria associated anemia is a major problem in malaria endemic areas, especially among children five years and below. Studies have shown that treating children with uncomplicated malaria with efficacious antimalarial drugs clears parasites, which prevents the depletion of red blood cells and thereby improving the Hb concentration levels. No study has been conducted in the Kassena-Nankana District of northern Ghana to determine the effect of antimalarial on the Hb of chi...
ABSTRACT The main purpose of this study was to examine the moderating effects of religious orientation and locus of control on the psychological phenomenon called learned haplessness. Six hundred (600) new entrant students into the Diploma in Applied Psychology programme of the University of Jos participated in the study. The study utilized the experimental design. Word anagram was used to induce and assess learned helplessness. It was hypothesized that, 1.participants who were externally con...
ABSTRACT Cryptosporidium is an intracellular zoonotic protozoan parasite that causes cryptosporidiosis, a diarrheal disease of humans and domestic animals. The parasite has been reported in a variety of domestic animals including dogs. Several species of Cryptosporidium infecting animals have also been reported in humans highlighting the zoonotic nature of the disease. This prospective cross-sectional study was carried out from January -: May, 20 1 8 in Six Area Councils of the FCT. Three war...