Medical & Health Sciences

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Medical & Health Sciences Research Papers/Topics

Evaluation of the Anti-diabetic And Antioxidant Potential of Methanolic Extract of Helianthus annuus L. Leaves in Alloxan-induced H yperglycemic Rats

Abstract This study evaluated the anti-diabetic and antioxidant potential of methanolic extract of Helianthus annuus L. leaves in alloxan-induced hyperglycemic rats. Fresh leaves of the plant were collected from their local habitat in the University of Nigeria, Nsukka environment. The extract was prepared by cold maceration using 80 % methanol at environmental temperature with intermittent sharing for 48 h to obtain a yield of 10.04 % w/w dry Helianthus annuus extract (HAE). The extract was t...

Effect of Aluminum – Magnesium Silicate (AMS) on Avian Influenza Virus Sub Type H5N1

ABSTRACT  Effect of Aluminium – Magnesium Silicate (AMS) on Avian Influenza Virus was tested in vitro by incubating an isolate of a highly pathogenic Avian Influenza Virus (AIV) involved in an outbreak of the disease in Nigeria, with a synthetic AMS. The isolate was a confirmed Influenza virus type A, subtype H5N1. Equal amount of the Virus sample and of the AMS, on volume to weight (v/w) basis, were incubated at room temperature for one hour and then centrifuged at 3000 revolutions per m...

Effects of a Combination of Artemether and Diminazen Aceturate Therapy on Experimental Trypanosoma brucei Infection in Rats

ABSTRACT This study investigated the effects of a combination of arthemether and diminazene aceturate therapy on experimental Trypanosoma brucei infection in albino rats. Thirty five male albino rats were used for the study. They were randomly assigned to seven groups of five rats each, after acclimatization. The groupings and their specific treatments were as follows: Group A- infected and treated with diminazene aceturate (DA) at the dose of 7.0 mg/kg body weight (bw) once on day 7 post-in...

Effects of Planes of Nutrition on Bodyweight, Hematology and Immune Response in Broiler Chickens Vaccinated with Newcastle Disease i-2 or Lasota Laccines

 ABSTRACT  The objective of this study was to investigate the effects of planes of nutrition on body weight, haematology and immune responses in broiler chickens vaccinated with NDV I-2 and Lasota vaccines. Two hundred (200) day old broiler chicks of Anak 2000 strain were used for the study. They were randomly assigned into nine groups of 20 birds each. Three feed types (A, B, C) were compounded for the study. Proximate analyses of the feeds were carried out. The groupings are A1 (feed A + ...

Effects of Varied Oral Doses of Trimethoprimsulfamethoxazole Therapy on The Thyroid Glands, Hematology, Serum Chemistry And Sperm Count in Nigerian Local Dogs

Abstract The effects of varied oral doses of trimethoprim-sulfamethoxazole therapy on the thyroid glands, haematology, serum chemistry and sperm count were evaluated in Nigerian local dogs. Twenty adult male dogs weighing between 4.5-10 kg were used for the study. The dogs were housed in metal cages in the Animal house of Department of Veterinary Parasitology and Entomology, University of Nigeria, Nsukka. The dogs were acclimatized for three weeks during which period they were vaccinated agai...

Prevalence of and Awareness of the Risks Associated with Antimicrobial Drug Residues in Edible Tissues of cattle and Pigs in Enugu State, Nigeria

ABSTRACT  This study was aimed at determining the prevalence of and awareness of health risks associated with antimicrobial residues (AMRs) in edible tissues of cattle and pigs slaughtered for human consumption in Enugu State. In the first phase, the awareness of public health problems associated with consumption of animal tissues containing AMRs and compliance to specified withdrawal period (WP) by livestock farmers and veterinary practitioners were determined. This was carried out using a ...

Comparison of Cotton Hair Thread(Ceiling Fan(R)) With Silk Suture on Experimentally Induced Wounds on Rabbits (Oryctolagus cunnicullus).

ABSTRACT Two protocols were used to investigate and compare the biocompatibility of the nonconventional suture material-Cotton Hair Thread (CHT) with conventional silk suture on experimentally induced wounds on rabbits. The results of the study in protocol I showed no significant difference(p > 0.05) in the means of, collagenization, vascularisation, reepithelialization, fibroblasts formation, polymorphonuclear leucocytes (PMNLs) and macrophage proliferation in groups A and B throughout the ...

Effects of Different Tissue Closure Techniques And Omentopexy on Incisional Wound Healing in West African Dwarf (WAD) Goats

ABSTRACT This study investigated the effects of different tissue closure techniques and omentopexy in incisional wound healing in West African Dwarf (WAD) goats. Twenty-five male WAD goats aged 6 – 8 months were used for this study. The mean anaesthetic induction, analgesic and surgery time (omentopexy) were: 2.71 ± 0.31, 25.96 ± 1.01 and 58.41 ± 3.20 minutes respectively for all the groups. Serosanguinous exudates were observed at the incision sites between PSD 1 – 8 in GPs A and D a...

Seroepidemiological Study of Brucella Abortus Antibodies in Cattle And Humans in Taraba State

ABSTRACT seroprevalence study of Brucella abortus antibodies was carried out in cattle and humans in Taraba State. The aim of the study was to determine the current status of B.abortus in cattle and humans and to find the distribution of the infection with respect to settled and nomadic herds, sex, breed, live and slaughtered cattle, geographical zones and occupation Two LGAs were randomly selected from each of the three senatorial zones totalling six LGAs. In each of the LGAs, 5 herds of ca...

The Anti-Inflammatory Activities of The Leaf Chloroform Extract of Palisota hirsute (K. Schum).

ABSTRACT  Ten plant samples were screened for topical anti-inflammatory activity. PDI.ra/n hi~w,u leaf (Family: Commelinaceae) gave the highest activity. A gradient solvent extraction of the leaf will conducted using petroleum ether (40" - 60"). cliloroforcn and methanol respectivel~. The different fractions were tested for anti-~nflarnrnalot-y activ~ty, and the chlorofor~n extract showed the highest effect. It was then subjected to f~~rtlier anti-inflammatory and analgesic tec15. using both...

Prevalence, Hematology Serum Biochemistry And Treatment of Procine Trypanosomiasis in Enugu North Senatorial Zone

Abstract A cross-sectional survey of trypanosome infection of pigs was carried out in three randomly selected Local Government Areas (Nsukka, Udenu and Igbo Eze South) out of the six local government areas in Enugu North Senatorial Zone. Blood samples collected at random from a total of 1800 pigs from abattoirs and farms were examined for trypanosomes using standard parasitological methods: wet film, buffy coat and Giemsa-stained thin smear preparations. The sensitivity of trypanosome isolat...

Effects of Oral Administration of Saccharomyces Cerevisiae on Enteric Methane Emission, Hematology, Serum Minerals, Forage Fractions Degradability And Production Parameters in West African Dw

ABSTRACT The effects of oral administration of Saccharomyces cerevisiae (SC) on enteric methane emission, haematology, serum minerals, forage fractions degradability and production parameters in West African Dwarf (WAD) sheep were studied using three treatment groups designated A, B, C and a control group D. Treatment groups A, B and C received 0.4, 0.6 and 0.8 grams SC per kilogram body weight (gSC/kgbw) respectively while group D served as control. Twenty adult female WAD sheep randomly di...

Development of an Experimental Rat Model For Studies on Sub- Acute Blood Anemia

ABSTRACT  Anaemia is one of the most clinically encountered conditions in animals and humans. It continues to be a global public health problem, affecting both developing and developed countries with major consequences for human and animal health as well as social and economic development. The objective of this study was to develop and test a rat model for experimental studies on sub-acute blood loss anaemia. The study design was an experimental research and development protocol, made up of ...

Antidiabetic Activities of The Methanolic Root Bark Extract of Afzelia Africana in Alloxan-Induced Diabetic Mice

ABSTRACT The methanolic root bark extract of Afzelia Africana was tested for antidiabetic activities in-vivo. The acute toxicity of the extract was tested in mice and the result showed that the extract 6 has low toxicity. Investigation on the phytochemical constituents of the plant extract revealed the presence of flavonoids, tannins, alkaloids, steroids and saponins. The plant extract was tested for antidiabetic activities in alloxan-induced diabetic mice at doses; 62.5 mg/kg, 125 mg/kg, 25...

Assessment of Urban Agriculture as A Means of Sustainable Urban Livelihood in Enugu Metropolis, Enugu State Nigeria

ABSTRACT Urban agriculture is defined as the practice of farming within the boundaries of towns or cities. It is one of the most common informal sector activities of urban dwellers in Enugu. Farming in this sense involves crop cultivation, animal rearing and fish farming. In this definition of urban agriculture, the location of farms plays the most important role. Approximately half of the residents in Enugu are involved in the practice. This is similar to the rates in other towns/cities in ...


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