Medical & Health Sciences

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Medical & Health Sciences Research Papers/Topics

Entandophragma angolense (WELW) CDC GUM AS A NOVEL BINDER AND MUCOADHESIVE COMPONENT IN ORAL TABLETS

ABSTRACT Mucoadhesive drug delivery systems are designed to prolong drug retention, thus offering advantages over conventional dosages through reduced dosage regimen and improved patient compliance. Natural polymers have gained importance over synthetic materials as excipients in such systems because they are less expensive, biocompatible and biodegradable. Entandophragma angolense gum (ENTA) is used in traditional medicine as a febrifuge, but its excipient properties have not been exploited...

Efficacy of herbal remedies used by herbalists in Oyo State Nigeria for treatment of Plasmodium falciparum infections a survey and an observation

ABSTRACT In the course of evaluating the contributions of phytomedicine to possible drug discovery of antimalarial drugs an ethnomedical survey of specialized children traditional clinics was done.

OBSTETRIC AND NEWBORN OUTCOMES AND RISK FACTORS FOR LOW BIRTH WEIGHT AND PRETERM DELIVERY AMONG HIV-INFECTED PREGNANT WOMEN AT THE UNIVERSITY COLLEGE HOSPITALIBAD AN

ABSTRACT There remains uncertainty about the impact of HIV on pregnancy outcomes and effects of highly active antiretroviral therapy on fetal development. This study describes obstetric outcomes among HIV positive patients at the University College Hospital, Ibadan. HTV positive patients were identified in the birth register. During the 30retrieval. The mean age of the HTV positive patients was 31.66 years (± 4.66); the mean gestational age at delivery was 38.02 weeks (± 2.75) and the m...

PATENCY OF DUCTUS ARTERIOUSUS IN NEWBORNS: EXPERIENCE IN A SPECIAL CARE BABY UNIT

ABSTRACT A prospective cohort study of infants admitted to the special care baby unit University College hospital Ibadan has revealed a 24.5 percent prevalence of patency of the ductus arteriousus among 97 infants who where admitted over a six month period.

HIV Infection among Newly Diagnosed TB Patients in Southwestern Nigeria: A Multi-DOTS Center Study

ABSTRACT Backgroud: The burden of TB and HIV infection is estimated to be about 512/100,000 and 3,000,000 people respectively. However, accurate data on TB/HIV co-morbidity in different parts of Nigeria were not available due to limited access to HIV Counseling and Testing (HCT) by individuals with TB infection. This study was designed to determine the true rate of HIV infection among newly diagnosed TB patients by providing comprehensive HCT services in 43 DOTS centers in Oyo State, Southwe...

MICROBIAL LOAD AND INDOOR AIR QUALITY OF OPERATING THEATRES IN THE UNIVERSITY COLLEGE HOSPITAL, IBADAN

ABSTRACT Microbial contamination of indoor air of operating theatres is one of the risk factors for the development of Surgical Site Infections (SSI). Operating theatre environment, including personnel, can become contaminated with microorganisms capable of causing SSI, morbidity, prolong hospitalization of patients or even death. Studies on indoor air quality particularly the air-borne microbes that are associated with SSI have not been adequately investigated. This study was therefore desi...

KNOWLEDGE AND USE OF ORAL REHYDRATION THERAPY AMONG MOTHERS OF UNDER-FIVE CHILDREN IN ODOGBO ARMY BARRACKS, IBADAN, NIGERIA

ABSTRACT Diarrhoeal diseases constitute a major cause of morbidity and mortality among under-five children in Nigeria. The knowledge and use of home therapies to manage diarrhoea using Oral Rehydration Therapy (ORT) with special reference to Sugar-Salt-Solution (SSS) are on the decline in recent times. However, knowledge and self-efficacy of nursing mothers in Nigerian army barracks relating to the use of ORT have not been fully studied. The study was designed to assess the knowledge of diar...

Indigenous surgical practices in rural southwestern Nigeria: implications for disease prevention

ABSTRACT A qualitative, community-based study was conducted in the rural community of Ago Are in southwestern Nigeria to learn about indigenous surgical practices and their potential for disease transmission. Community leaders as key informants assisted in identifying two types of indigenous practitioner whose work involved blood contact, whose work was observed. The ol6lil are surgeons who specialize in circumcision and making traditional facial-markings, while the generic term for healer, o...

Evaluation of Renal Blood Flow Using Doppler Sonography in Children with Acute Falciparum Malaria in South-Western Nigeria

ABSTRACT Renal blood flow evaluation during malaria illness is rarely done despite the high incidence of kidney injury from malaria and availability of Doppler Ultrasound in malaria endemic areas.

THE VIROLOGY AND DYNAMICS OF THE EPIDEMIC

ABSTRACT Viruses are submicroscopic, obligate intracellular parasites that can neither grow nor reproduce outside a living cell. Their survival therefore depends completely on the continued survival of their hosts.

PITFALLS IN DIAGNOSIS OF HEPATITIS B VIRUS INFECTION AMONG ADULTS NIGERIANS

ABSTRACT Objective: Hepatitis B virus infection is common in Nigerians and its diagnosis is necessary for effective treatment and eradication. This study is aimed at highlighting the serological factors jeopardizing the diagnosis and treatment of the infection among Nigerians adults.

EFFECTS OF GNETUM AFRICANUM WELW. AND OCIMUM GRATISSIMUM LINN. AQUEOUS LEAF EXTRACTS ON THE HAEMATOLOGICAL AND BIOCHEMICAL CHANGES IN CYANIDE-TREATED RATTUS RATTUS

ABSTRACT Cyanide toxicity is of public health concern. Cyanide is among the most potent and deadly poisons and sources of potential human exposure to it are numerous, arising through its release into the environment from both natural and anthropogenic sources. Gnetum Africanum (GA) and Ocimum Gratissimum (OG) which contain essential amino acids required to abate cyanide toxicity effects, are widely used local plants for both nutritional and therapeutic purposes in Nigeria. There is dearth of...

Clinicoradiologic and Sonographic Patterns of Metastasis in Hepatocellular Carcinoma

ABSTRACT Hepatocellular carcinoma (HCC) is usually diagnosed at an advanced stage, when little remedy could be offered. There is a need for relatively affordable, available and noninvasive tests for diagnosis, staging and detection of metastasis among individuals at risk. A clinical, chest radiographic (CXR) and abdominal ultrasonographic examination was carried out to detect and evaluate the pattern of metastasis among 53 untreated patients. One patient had clinical paraparesis with no outwa...

Normal Sonographic Dimensions for Liver, Spleen and Kidneys in healthy South West Nigerian Children-A pilot study

ABSTRACT Ultrasonographic measurement of abdominal organ dimensions in children of all ages is utilized in the monitoring of abdominal organ growth pattern, diagnosis and follow-up of patients with a variety of diseases. Base line reference values are necessary to determine abdominal organ growth and the degree of deviation from the normal in pathological states. 

Sociodemographic Factors and Clerkship Experience Influence Ibadan Medical Students' Preference for Radiology Specialty

ABSTRACT Over the years, there has been a significant rise in the number of graduates from medical schools in subSaharan Africa. A recent study of 105 selected medical schools found an increase from about 8,000 graduates in 2008 to >18,000 in 2011 .


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