Medical & Health Sciences

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Medical & Health Sciences Research Papers/Topics

Can encroached rangelands enhance carbon sequestration in the African Savannah?

Abstract: Climate change and bush encroachment pose huge challenges to rangeland management in Namibia. These challenges require a holistic management approach that ensures consistent and optimum forage productivity and sustainability. Mechanical and chemical control methods are the most used techniques in controlling woody encroaching species to improve pastoral properties in the Namibian savannas. However, there is very little information regarding the management options that concurrently ...

The effect of climate variability in the efficacy of the entomopathogenic fungus Metarhizium acridum against the desert locust Schistocerca gregaria

Abstract: Despite substantial efforts to control locusts they remain periodically a major burden in Africa, causing severe yield loss and hence loss of food and income. Distribution maps indicating the value of the basic reproduction number R0 was used to identify areas where an insect pest can be controlled by a natural enemy. A dynamic process-based mathematical model integrating essential features of a natural enemy and its interaction with the pest is used to generate R0 risk maps for in...

Developing low-cost house floors to control tungiasis in Kenya – a feasibility study

Abstract: Context Tungiasis is a neglected tropical skin disease endemic in resource-poor communities. It is caused by the penetration of the female sand flea, Tunga penetrans, into the skin causing immense pain, itching, difficulty walking, sleeping and concentrating on school or work. Infection is associated with living in a house with unsealed earthen house floors. Methods This feasibility study used a community-based co-creation approach to develop and test simple, locally appropriate, a...

Socioeconomic burden of trypanosomiasis: Evidence from crop and livestock production in Ethiopia

Abstract: This paper estimates the impact of trypanosomiasis on crop-livestock production, economic loss and poverty in Ethiopia. We use unique panel data to estimate how the disease affects livestock deaths, production costs and crop production. We then use these estimates to evaluate the disease's total economic loss and its implications on poverty in the study districts and the country. Estimates of the fixed effect regression models indicate that trypanosomiasis increases the value of li...

Plant-Feeding Behaviour and its Efects on the Fitness and Competence of the Malaria Vector Anopheles Gambiae (Diptera: Culicidae)

Abstract: Malaria remains a serious threat in sub-Saharan Africa Available control tools are now largely ineffective. Because of the role of vectors in malaria transmission, integrated vector management strategies that are environmentally safe, economically feasible and acceptable to resource-limited communities are one way to achieve effective malaria control. However, adequate knowledge of the biology, behaviour and ecology of the malaria vectors are imperative. Sugar-feeding from plants i...

Development of formulations and delivery systems to control economically important ticks with entomopathogenic fungi

Abstract: Due to the rapid development of tick resistance to synthetic chemical acaricides and the potential risk posed by these chemicals to non-target species, efforts are intensifying towards the development of entomopathogenic fungi as an environmentally benign alternative tick control strategy. The main objective of this study is the development of formulations and delivery systems for control of ticks with entomopathogenic fungi. Screening of entomopathogenic fungal isolates is the fir...

Ecology and Management of the Leafhopper Vectors (Cicadulina Spp.) of Maize Streak Virus

Abstract: Several Cicadulina species are important pests of maize by virtue of their role as vectors of maize streak virus (MSV). Tnis study deals with various aspects of the vector/virus/host plant relationship. Developmental times for all life stages of both C. anestae and C. mbila were inversely related to temperature, and the data were used to develop a degree-day (DD) model that can be used to estimate population growth in the field. The rate of development peaked at 30 °c for both spe...

Varroa destructor virus 1: A new picorna-like virus in Varroa mites as well as honey bees

Abstract: Honey bees are important insects that have benefited mankind for medicinal and nutritional purposes for thousands of years. They have also provided an important balance in the environment allowing many plant species to pollinate and proliferate. Honey bees have naturally occurring parasites and pathogens which usually do not destroy the bees. The development of long-distance travel among human beings introduced global trade in plants and animals introducing new species and diseases...

Studies on the Immune Response to Amblyomma Variegatum in Cattle and the Effects of Haemoparasitism on the Acquisition of Tick Resistance

Abstract: Acaricides in tick control, had been thought to be in Africa the panacea for over a century. Environmental and economic constraints, development of acaricide-resistant strains due to acaricide misuse, have brought about the need for an alternative tick control strategy. The use of tick resistant cattle has then been advocated and echoed in the USA and Australia where it got its full expansion. In Africa, few works have been undertaken on tick resistance despite the fact that many t...

Combining malaria control with rural electrification: Social and behavioural factors that influenced the design, use and sustainability of solar-powered mosquito trapping systems (SMoTS) for

Abstract: The research on which this thesis is based was carried out as part of a multidisciplinary project, “SolarMal”, which aimed to evaluate proof of principle for the elimination of malaria from Rusinga Island by augmenting the existing national malaria control programme tools with mass trapping of mosquitoes. As electricity was required to run the mosquito traps and most residents had no electricity, solar systems were also installed,providing lighting and telephone charging as wel...

Differential attractiveness of humans to the African malaria vector Anopheles gambiae Giles: Effects of host characteristics and parasite infection.

Introduction: Malaria in man is caused by four species of protozoan parasites1 belonging to the genus Plasmodium. Plasmodium parasites exhibit a complex life cycle involving development through two host2 species: an insect vector3 (definitive host4) and a vertebrate species (intermediate host5). Humans serve as intermediate hosts for several Plasmodium species (P. falciparum, P. vivax, P. ovale and P. malariae) whilst female mosquitoes of the genus Anopheles serve as the definitive hosts (Fi...

Occurrence of Rift Valley Fever and Associated Risk Factors in Cattle in Ijara District, Kenya

Abstract: Ijara district in Kenya was one of the hotspots of Rift Valley Fever (RVF) during the 2006/2007 outbreak which led to human and animal deaths causing huge economic losses. The main constraint in the control and prevention of RVF is inadequate knowledge on its occurrence during the interepidemic period. This study was aimed at understanding the occurrence of RVF and perceived risk factors by pastoralists in cattle in Ijara to enable the development of improved community-based diseas...

A Surveillance Study on Tick and Tick-Borne Pathogen diversity in Shimba Hills National Reserve, Kenya

Abstract: Outbreaks of emerging and re-emerging tick-borne pathogens are becoming more frequent worldwide. Surveillance is critical to improve our understanding of pathogen diversity and their tick vectors. This will elucidate disease transmission dynamics that can inform the development of better disease prevention and control strategies. A total of 4,324 questing ticks (209 adult ticks, 586 nymphs and 3,502 larvae) were collected from six sites in Kenya‟s Shimba Hills National Reserve (S...

Determinants of Malaria in Irrigated and Non-irrigated Villages of Mwea: a Comparative Assessment

Abstract: Today, approximately 40% o f the world’s population, mostly those living in the poorest countries, are at risk of malaria, which causes more than 300 million acute illnesses and at least one million deaths annually. Ninety per cent o f deaths due to malaria occur m subSaharan Africa, mostly among young children. The importance o f malaria cannot be over emphasized. A project, (Agro-ecosystem Management for Community-Based Integrated Malaria Control in East African Irrigation Sche...

In Silico and Molecular Analysis of Xpta Protein Toxin Genes of Xenorhabdus Sp. and Efficacy of the Bacterium on Sitophilus Zeamais and Prostephanus Truncatus

Abstract: Bacteria of the genus Xenorhabdus are entomopathogens that produce insecticidal protein toxins against a wide range of insects. The main proteins involved are the Xenorhabdus protein toxins (Xpts), categorized as class A, B and C. They work best as a complex, though individually, XptA has been found to be more potent against some insect pests such as Pieris brassicae and Heliothis virescens. The maize weevil (Sitophilus zeamais) and the larger grain borer (Prostephanus truncatus) a...


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