Natural & Applied Sciences

Natural & Applied Sciences Research Papers/Topics

Potential Genotoxicity, Hematotoxicity and Clastogenicity of Three Commonly Consumed Polyherbal Formulations in Abeokuta South-West Nigeria

Background:  The  current  upsurge  in  the  use  of  polyherbal  remedies  and  coupled  with  loose  regulation  on  public access  to  these  products  underscore  research  efforts  to  evaluate  their  biochemical  effect,  noting  also  that  many  of  the polyherbal  medicines  lack  scientific  evidence  to  support  their  medicinal  claims.  Objective:  We  therefore  investigated  the potential  genotoxicity,  hematotoxicity  and  ...

MOBILE TICKETING SYSTEM USING RAILWAY TRANSPORT SYSTEM AS A CASE STUDY

TABLE OF CONTENTS   CONTENTS                                                                                                PAGES   Title page-----------------------------------------------------------------------------------------------------i Certification--------------------------------------------------------------------------------------------------ii    Dedication--------------------------...

Extra-pulmonary oxidative stress investigations of an over-the-counter pyrethroid insecticide product in rats

Extra-pulmonary  oxidative  stress  investigations  of  exposure  to  aerosol,  of  an  over-the-counter pyrethroid  insecticide  product  in  Nigeria  in  Wistar  rats  were  carried  out.  Four  groups  of  five  animals each  were  used  in  this  study,  and  were  exposed  to  different  concentrations  of  the  insecticide  aerosol. Malondialdehyde  (MDA)  and  reduced  glutathione  (GSH)  concentrations  were  determined  in  the  live...

Edible camphor-induced histopathological changes in hippocampus and cerebral cortex following oral administration into rats

Introduction:  Raw edible camphor (EC), and as component of herbal infusions  are widely used to treat pile, back pain, erectile dysfunction, and as  an aphrodisiac especially in preparation  for sexual intercourse by men. It has been traced in umbilical cord, blood,  fetal, adipose,  and other tissues including brain, where it bioaccumulates.  Methods:  The study, therefore, investigated the possible histopathological changes  in brain, heart, and  spleen that may result following ...

Induction of micronuclei in bone marrow cells and hepatotoxicity of one of the most common over-the-counter pyrethroid insecticide products in Nigeria

Increasing environmental pollution in the tropics is creating a breeding ground for mosquitoes, leading to increasingly frequent use of insecticides to combat home infestation of mosquitoes, the vector of malarial parasites. Household members are therefore more prone to aerosol exposure and subsequent health effects. We assessed the hepatotoxic and clastogenic effects in rats exposed to different levels of aerosols of one of the insecticides most commonly in used in Nigeria. There were signif...

ANTICLASTOGENIC AND HEPATOPROTECTIVE PROPERTIES OF GINGER (ZINGIBER OFFICINALE) EXTRACT AGAINST NITROBENZENE-INDUCED TOXICITY IN RATS

Ginger  or  Zingiber  officinale  has  been  reported  to  possess  antioxidant  activities  that  can protect  against  free  radical  damage.  We  therefore  carried  out  this  study  to  investigate  the  possible ameliorative  effects  of  ginger  against  the  clastogenicity,  hepatotoxicity  and  oxidative  stress  induced by  nitrobenzene  (NB)  administration  in  wistar  rats.  Twenty  male  wistar  rats  were  divided  into  four g...

ROLE OF CIRCADIAN CLOCK GENES IN THE REGULATION OF CELL CYCLE PROCESSES

One  interesting  branch  of  biochemistry  which  scientists  are  still  trying  to completely  unravel is the  area  of  chronobiochemistry.  The  history  of  chronobiology  is  dated  400  B.C.,  when  Androsthenes observes  that  leaves  of  certain  trees  open  during  the  day  and  close  at  night.  It  was  only  recently  that the  first  human  clock  gene  was  discovered.  All  living  organisms  possess  an  internal  bio...

Effect of edible camphor administrations on levels of steroid and thyroid hormones in male wistar rats_content_1

ABSTRACT Background:  Edible  camphor  (EC)  is  one  of  the  ingredients  in  the  preparation  of  local infusion  for  the  management  and  treatment  of  pile,  back  pain,  and  erectile  dysfunction, which  are  practices  commonly  in  the  south-western  part  of  Nigeria.  Methods:  Thirty  rats  were  used  for  the  study,  and  were  divided  into  six  groups  of  five rats  each.  Group  I  animals  served  as  normal  ...

Design and Implementation Of E-Library System (A case study of University of Port-Harcourt)

ABSTRACT Libraries have been an important part of educational and information sector of any school or community. The success of any library largely depends on proper management. Several libraries have suffered failure as a result of inadequate management and incapacitations in handling sensitive information as regards members of the library.  This research therefore, aimed at developing a digital library system, which will help direct and position library to meets its ever increasing deman...

THE EFFECT OF ABATTOIR EFFLUENT ON PHYSICOCHEMISTRY AND BACTERIOLOGICAL ANALYSIS ON KARU RIVER, ABUJA (CASE STUDY: KARU ABATTOIR)

The impact of Sewage and Abattoir effluent discharge into river resulted in water pollution there by reduces it quality.This study aimed at analysing the physicochemical and bacteriological parameters of Karu Abattoir effluent and Sewage discharge into Karu River in FCT ,Abuja, Nigeria in order to ascertain the quality and impact on Karu River. Four water samples along with one effluent ample were collected aseptically and subjected to standard microbiological and physicochemical analysis

R Program to Calculate Mathematical Interest Theory

R program that calculate mathematical interest theory such as dollar weighted yield rate, time weighted yield rate, simple and compound interest  and all others.

Heterocyclics Compound Effects in Crude Oil

PREFACE Crude oil is a naturally occurring brown to black flammable liquid which is composed of hydrocarbon compounds, non hydrocarbon compounds, organometallic compounds. Various types of non hydrocarbon compounds present in crude oil are organic sulfur, nitrogen and oxygen compound. Traces of this compound causes problem to catalytic refining process in the refining industry. Hydro treatment process is used to eliminate the problems caused by this compound TABLE OF CONTENT  Abstract  CHAP...

Role of mitochondria in apoptosis

In  living  cells,  especially  eukaryotes,  mitochondria  involvement  appears  to  be  important in  the  general  status  of  every  aspect  of  life.  Apoptosis  as  a  programmed  cell  death  is  mandatory to  all  life  process  thus,  mitochondria  might  be  describe  as  organelles  that  serves  as  a  gatekeeper to  trap  a  variety  of  proapototic  protein  and  prevent  the  functions  of  this  proteins  in  the  cytosol...

GENETICS OF EPILEPSY

Genetics is a huge and growing area across human biology, medicine and science, providing information about basic processes from birth to death, from development to degeneration, and in even revealing enough about disease biology to lead to new therapies or better use of existing treatments because gene activity underlines all biological process (Sisodiya, 1881; Vadlamudi et al., 2014).  Epilepsy is defined as one unprovoked (or reflex) seizure and a probability of further seizures similar t...

INTERACTIVE INSTRUCTIONAL MATERIAL IN C PROGRAMMING

The study focused on the development of Interactive Instructional Materialfor C++ Programming Language. The primary objective of the study is to develop and evaluate the interactive instructional material. The study will be conduct in the second semester of school year 2016-2017 at the College of Computer Studies in University of Rizal System Binangonan Rizal.


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