ABSTRACT Recently, there has been a considerable attention on modeling overdispersed binomial data that occur in toxicology, biology, clinical medicine, epidemiology and other related fields using a class of Binomial mixture distribution. Specifically, Beta-Binomial (BB) and KumaraswamyBinomial distribution (KB) in this class have been extensively used to model the overdispersed Binomial outcomes. A new three parameter binomial mixture distribution namely, McDonald Generalized Beta-Binomial ...
ABSTRACT Maize production in sub-Saharan Africa remains low and the yields are on the decline. This has been attributed to a variety of factors which include soil nutrient depletion and Striga infestation. Soil phosphorous, nitrogen and Striga hermonthica are the major constraints to maize production in Nyanza Province of Kenya. The yields are typical of low input systems ranging below 1.0 t ha-1 against a potential of 5.0 t ha-1 per season. In an attempt to overcome these constraints, field...
ABSTRACT Vector control in the highlands of western Kenya has resulted in a significant reduction of malaria vectors. This has made the current entomological parameters being used to measure transmission to become insensitive and challenging. Antibodies to the Circum-sporozoite protein (CSP) have been associated with transmission intensity and have corresponded well with EIR. The study objective was to determine the association between the level of circum-sporozoite protein and merozoite sur...
ABSTRACT Cassava brown streak disease (CBSD) is an important disease causing losses of up to 70% in the most susceptible cultivars. Its effects include: reduced root quality due to pitting, root constriction and necrosis, and reduced number and weight of tuberous roots. To contribute to CBSD management, a study was conducted to: (i) Screen East African cassava landraces and F1 populations for CBSD resistance; (ii) Analyse symptom expression and virus accumulation in CBSV graft inoculated cas...
ABSTRACT Tea industry in Kenya forms the largest agribusiness contributing up to 4% of the country’s gross domestic product and over 26% of total foreign exchange earnings. However, significant revenue is lost when tea is sold in undiversified form. Therefore, this study aimed at determining the biochemical diversity in Kenyan tea clones and their potential for diverse product development. Samples were obtained from 197 tea clones conserved in Kericho and Kangaita substation and assayed fo...
ABSTRACT Lake Naivasha is a freshwater lake located about 80 km northwest of Nairobi and lies about 1890 metres above sea level. The freshwater system is used for drinking, washing and livestock watering by more than 600,000 people. However, declining water quality due to environmental perturbations has raised public concerns worldwide. The occurrence of blooms of cyanobacteria has become a serious problem as they produce a wide spectrum of toxins including microcystin which cause various ad...
ABSTRACT Microbial infections remain to be a major global public health challenge. In Kenya, these infections cause significant morbidity and mortality. Their devastating effects are majorly attributed to antimicrobial drug resistance. Nonetheless, the biodiversity and ecology of tropical Basidiomycetes fungi is an untapped source of potential bioactive compounds. Therefore, the current study aimed to isolate and test crude extracts and antimicrobial compounds from Basidiomycetes against sel...
ABSTRACT Different communities in Kenya use a wide variety of indigenous plants for food. About 850 species of plants are used for food. To this group belong Amaranthus species that has important nutrients and a rich array of biologically active secondary metabolites. Corriandrum sativum is a leafy spice/ herb that contain volatile oils from which it derives its flavour and aroma and also antimicrobial properties. Essential oils from fresh leaves of C. sativum were extracted by hydro distill...
Abstract The growth of Candida utilis NRRL Y-1084 in acid and enzymatic hydrolysates of cassava peel and on glucose in a mineral salts medium was investigated in aerobic submerged cultivation. Kinetic and stoichiometric parameters for growth were determined. The cardinal temperatures of this yeast strain were 14 °C, 33 °C and 41 °C. C. utilis exhibited no absolute requirement for growth factors, although its maximum specific growth rate (μmax) was higher in the mineral salts medium with y...
ABSTRACT Cassava (Manihot esculenta) grows well in Tropical and Sub-Tropical regions of Sub-Saharan Africa. It is used as a food and raw material for many industrial applications, including food, feed and starch. Cassava has several varieties whose physico-chemical properties and functional properties of flour are hardly known. The aimed at characterizing physico-chemical and functional properties of cassava flour from different varieties harvested at different maturity stages and to determi...
ABSTRACT The abundance of indigenous leafy vegetables (ILVs) during rainy seasons and accompanying poor storage systems leads to high post-harvest losses (PHL). These gluts in the rainy seasons are usually followed by scarcity in the dry seasons. Currently some limited preservation is employed involving boiling of ILVs and open sun drying, a practice that is inappropriate and done under unhygienic conditions. To reduce the huge losses, a cheaper, hygienic and locally adaptable preservation m...
ABSTRACT Fluorosis is a condition caused by excessive intake of fluoride, and is characterized mainly by mottling of teeth. A number of defluoridation techniques have been proposed, studied and even implemented in a number of countries, to varying degrees of success. Among these techniques, contact precipitation, a hybrid technique involving the use of calcium and phosphate compounds together with bone char to effect defluoridation of water has been extensively used. The mechanism of fluorid...
ABSTRACT Innate immunity has a key role in the control of microbial infections in both vertebrates and invertebrates. In insects, including vectors that transmit parasites that cause major diseases such as trypanosomosis, leishmaniasis and filariasis, antimicrobial peptides and agglutinins form an important component of innate immunity and participate in regulating parasite development. In this study, induced haemolymph peptides from a non-vector, nonheamatophagous insect, Schistocerca grega...
ABSTRACT Mosquitoes present a worldwide, public health and nuisance challenge since they transmit human diseases including west Nile virus, malaria, dengue, Japanese encephalitis, filiarisis and other viral diseases throughout the globe. An obvious method for preventing the spread of these diseases is to control mosquito vector population by insecticides and synthetic agents, which have been developed and employed in the field with considerable success. As a result of insects’ resistance a...
Summary This short report describes the results of a rapid; simple and cost effective immuno diagnostic test for malaria in Ibadan, Nigeria. A total of 77% patients presenting at the children outpatient clinic, University College Hospital with malaria symptoms were screened for malaria parasites by microscopy using Giemsa stain and by the immuno chromatographic card test. The immunodiagnostic test had a sensitivity of 93.1 % and a specificity of 95.8%, making a gog,d alternative for malaria ...