ABSTRACT This study was conducted to document the occurrence and characteristics of mycotic agents isolated from trade horses and donkeys in Obollo-Afor, Enugu State. A total of 497 horses and 65 donkeys presented for sale at Obollo-Afor horse/donkey market during the wet season (June to August 2014) and dry season (January to March 2015) were examined for skin lesions. For each horse/donkey examined, the location of skin lesion as well as the sex of the animal was recorded. Each skin lesion...
ABSTRACT The high turn-over rate and quest for white meat have given more impetus to poultry production. The need to increase production and meet the demand for poultry meat has necessitated the use of veterinary drugs, especially antimicrobials, for therapeutic, prophylactic and growth promotion purposes in poultry farming. These drugs tend to accumulate in tissues and organs as residues. The presence of drug residues in tissues above the maximum residue limit (MRL) becomes violative if wit...
ABSTRACT SUMMARY Objective: To determine patients' perceptions abou t the quality of care and possible factors that q'lay prevent adequate utilization of services at the study centre and therefore make recommendations for improvement in service utilization. Materials and methods: A cross sectional survey of patients from the Eye Clinic and Eye Ward of the University College Hospital. Ibadan, was carried out using a standardized questionnaire between May and June 2001. Results: A total of fi...
ABSTRACT Traditional Birth Attendants (TBAs) are lay persons who attend to deliveries and concerted efforts have been made to train them. Anecdotal reports suggest that many expectant mothers patronize TBAs in Ibadan. However, there is dearth of information relating to the TBAs’ maternal care knowledge and practices. This study was therefore conducted to assess TBAs’ knowledge and practices relating to maternal care in Ibadan, Oyo State. A cross-sectional survey of 407 out of 608 TBAs who...
ABSTRACT The methanolic root bark extract of Afzelia Africana was tested for antidiabetic activities in-vivo. The acute toxicity of the extract was tested in mice and the result showed that the extract 6 has low toxicity. Investigation on the phytochemical constituents of the plant extract revealed the presence of flavonoids, tannins, alkaloids, steroids and saponins. The plant extract was tested for antidiabetic activities in alloxan-induced diabetic mice at doses; 62.5 mg/kg, 125 mg/kg, 25...
Abstract Background: The World Health Organisation (WHO) guidelines for the control of malaria during pregnancy include prompt and effective case management of malaria combined with prevention of infection by insecticide-treated nets (ITNs) and intermittent preventive treatment in pregnancy (IPTp). Despite this the uptake is poor. Objective: To describe the malaria prevention measures utilized by these women in this environment. Methods: Information was obtained from consented pregnant and ne...
ABSTRACT Effect of stabilizing chloroquine phosphate in a synthetic Aluminium Magnesium silicate (Nanoparticles) on the antiplasmodial activity of the drug was investigated. Mice infected with Plasmodium berghei were treated with chloroquine phosphate at 7 mg/kg, 5 mg/kg and 3 mg/kg dose levels respectively. Two subgroups at each dose level were treated with chloroquine phosphate alone and with a drug formulation of 20% chloroquine phosphate in the synthetic Aluminium Magnesium Silicate (AMS...
ABSTRACT Controlled release floating metformin hydrochloride microbeads were prepared and optimized using a blend of varying concentrations of freeze-dried pregelatinized Chinese yam starch (Dioscorea oppositifolia L) and sodium alginate. Floating microbeads were prepared by the ionotropic gelation method using 10% w/v calcium chloride as the cross-linking agent and sodium bicarbonate as the gas releasing agent. A full 32 factorial design was used to investigate the influence of two variables...
ABSTRACT Diabetes mellitus is a group of metabolic disorders characterized by chronic hyperglycemic condition resulting from defects in insulin secretion, insulin action or both. It is a growing public health concern worldwide affecting humans and animals. Synthetic drugs available for the treatment of the ailment have serious side effects, complicated mode of intake and are costly. Literature search revealed that Cussonia arborea is used folklorically in the management of Diabetes mellitus....
ABSTRACT Fifteen dogs of similar age (8-12 months) were used for the clinical study. They were randomized into 3 groups (CH1-5, CL1-5 AND AC1-5). Simple transverse femoral fractures were created under anaesthesia using a bone saw. Spatial alignment of the bone was achieved by insertion of an intramedullary pin. Radiographic assessment confirmed that the pins were intact and internal fixation was thorough. Celecoxib (Celebrex® Pfizer Inc, Germany) was supplied in encapsulated powdered form a...
ABSTRACT The toxicology of six suspected poisonous plants Leucaena leucocephala Benth, Tribulus terrestris Linn Eugenia uniflora Linn, Dichapetalum madagascasience Poir, Lantana camara Linn, and Solanum torvum Benth); were evaluated in Sprague Dawley rats weighing between 200-300 grams. Two of these plants, Lantana camara and ~. madagascasience were re-evaluated in West African dwarf goats. Spectrophotometric and titrimetric methods were also used to determine some inorganic and metallic cont...
ABSTRACT This study was carried out to evaluate the chemical composition and bacterial load of donkey meat as well as the prevalence of verotoxigenic Escherichia coli (VTEC). The study adopted the survey and experimental designs. A questionnaire, which comprised three sections, was developed to elicit information on the demographics, source of meat, and factors that influence choice of meat consumed by the respondents. The instrument for data collection was validated by three experts. A pilo...
ABSTRACT Nigeria has an annual population growth rate of 2.6 and a relatively high Total Fertility Rate (TFR) of 5.6 due to its larger family size. Men‟s fertility desire is a strong determinant of family sizes, but it is women that perform greater share of childcare activities. The potential relationship between the desire for childbearing and the responsibility of early childcare between spouses has not been adequately explored. This study was therefore designed to determine the extent to...
ABSTRACT The contractile activity of M. pruriens and the relaxatory property of C. odorata was investigated using in vitro methods in the rat. M. pruriens caused a dose-dependent increase in uterine muscle contraction with a maximum peak in amplitude with 0.57 mg/ml of the extract and an EC50 of 2.7 mg/ml. The contraction was unaffected by atropine sulphate (0.042 µmol), but abolished by isoprenaline (0.06-0.23 µmol), salbutamol (0.012-0.4 µmol) and adrenaline (16 nmol).Uterine muscle con...
ABSTRACT The purpose of this study was to identify the factors that affect clinical training of nursing students in School of Nursing Afikpo in Ebonyi State and Department of Nursing Sciences, University of Nigeria, Enugu Campus in Enugu State. Four research questions and three null hypotheses guided the study. The research design used was descriptive cross-sectional survey method. A face and content validated questionnaire with 34 items was used for the collection of data. Data derived from...