Abstract: Malaria remains a serious threat in sub-Saharan Africa Available control tools are now largely ineffective. Because of the role of vectors in malaria transmission, integrated vector management strategies that are environmentally safe, economically feasible and acceptable to resource-limited communities are one way to achieve effective malaria control. However, adequate knowledge of the biology, behaviour and ecology of the malaria vectors are imperative. Sugar-feeding from plants i...
Abstract: Due to the rapid development of tick resistance to synthetic chemical acaricides and the potential risk posed by these chemicals to non-target species, efforts are intensifying towards the development of entomopathogenic fungi as an environmentally benign alternative tick control strategy. The main objective of this study is the development of formulations and delivery systems for control of ticks with entomopathogenic fungi. Screening of entomopathogenic fungal isolates is the fir...
Abstract: Several Cicadulina species are important pests of maize by virtue of their role as vectors of maize streak virus (MSV). Tnis study deals with various aspects of the vector/virus/host plant relationship. Developmental times for all life stages of both C. anestae and C. mbila were inversely related to temperature, and the data were used to develop a degree-day (DD) model that can be used to estimate population growth in the field. The rate of development peaked at 30 °c for both spe...
Abstract: Honey bees are important insects that have benefited mankind for medicinal and nutritional purposes for thousands of years. They have also provided an important balance in the environment allowing many plant species to pollinate and proliferate. Honey bees have naturally occurring parasites and pathogens which usually do not destroy the bees. The development of long-distance travel among human beings introduced global trade in plants and animals introducing new species and diseases...
Abstract: Acaricides in tick control, had been thought to be in Africa the panacea for over a century. Environmental and economic constraints, development of acaricide-resistant strains due to acaricide misuse, have brought about the need for an alternative tick control strategy. The use of tick resistant cattle has then been advocated and echoed in the USA and Australia where it got its full expansion. In Africa, few works have been undertaken on tick resistance despite the fact that many t...
Abstract: The research on which this thesis is based was carried out as part of a multidisciplinary project, “SolarMal”, which aimed to evaluate proof of principle for the elimination of malaria from Rusinga Island by augmenting the existing national malaria control programme tools with mass trapping of mosquitoes. As electricity was required to run the mosquito traps and most residents had no electricity, solar systems were also installed,providing lighting and telephone charging as wel...
Introduction: Malaria in man is caused by four species of protozoan parasites1 belonging to the genus Plasmodium. Plasmodium parasites exhibit a complex life cycle involving development through two host2 species: an insect vector3 (definitive host4) and a vertebrate species (intermediate host5). Humans serve as intermediate hosts for several Plasmodium species (P. falciparum, P. vivax, P. ovale and P. malariae) whilst female mosquitoes of the genus Anopheles serve as the definitive hosts (Fi...
Abstract: Ijara district in Kenya was one of the hotspots of Rift Valley Fever (RVF) during the 2006/2007 outbreak which led to human and animal deaths causing huge economic losses. The main constraint in the control and prevention of RVF is inadequate knowledge on its occurrence during the interepidemic period. This study was aimed at understanding the occurrence of RVF and perceived risk factors by pastoralists in cattle in Ijara to enable the development of improved community-based diseas...
Abstract: Outbreaks of emerging and re-emerging tick-borne pathogens are becoming more frequent worldwide. Surveillance is critical to improve our understanding of pathogen diversity and their tick vectors. This will elucidate disease transmission dynamics that can inform the development of better disease prevention and control strategies. A total of 4,324 questing ticks (209 adult ticks, 586 nymphs and 3,502 larvae) were collected from six sites in Kenya‟s Shimba Hills National Reserve (S...
Abstract: Today, approximately 40% o f the world’s population, mostly those living in the poorest countries, are at risk of malaria, which causes more than 300 million acute illnesses and at least one million deaths annually. Ninety per cent o f deaths due to malaria occur m subSaharan Africa, mostly among young children. The importance o f malaria cannot be over emphasized. A project, (Agro-ecosystem Management for Community-Based Integrated Malaria Control in East African Irrigation Sche...
Abstract: Bacteria of the genus Xenorhabdus are entomopathogens that produce insecticidal protein toxins against a wide range of insects. The main proteins involved are the Xenorhabdus protein toxins (Xpts), categorized as class A, B and C. They work best as a complex, though individually, XptA has been found to be more potent against some insect pests such as Pieris brassicae and Heliothis virescens. The maize weevil (Sitophilus zeamais) and the larger grain borer (Prostephanus truncatus) a...
Abstract: Xenorhabdus spp. (Enterobacteriaceae) are endosymbionts of entomopathogenic nematodes from the Steinernema genus. They cause insect mortality by producing potent insecticidal toxin complexes composed of XptA1, XptA2 (class A), XptB1 (class C) and XptC1 (Class B) proteins. However, the use of only the bacterium as a biopesticide is limited as they depend on their nematode hosts for survival in the environment. The XptAs exhibit different spectra of activity, requiring XptB1 and XptC...
Abstract: Tsetse and trypanosomosis have been extensively studied and an array of vector and disease control measures have been developed and applied with varying degrees of success. Current trypanosomosis control strategies rely on use of trypanocidal drugs, breeding of trypanotolerant cattle and tsetse control or eradication. Since none of these control options has proved to be a fully viable solution to the control of trypanosomosis, search for more tsetse fly and trypanosomosis control m...
Abstract: Malaria is one of the public health problems facing people in many parts of Kenya including semi-arid areas. It is caused by an infectious bite of female Anopheles mosquitoes. To effectively implement malaria control program, the knowledge of colonization, resting behavior of the vectors and effect of distance between houses and breeding habitats on mosquito abundance is required. This research set out to determine seasonal dynamics, outdoor resting habits and colonization of larva...
Abstract: Susceptibility of Ae. aegypti mosquito to dengue virus (DENV) varies geographically and can be influenced by climatic factors such as temperature, which affect the incidence, seasonality and distribution of vector-borne diseases. The first outbreak of dengue fever (DF) in Kenya occured in 1982 in the coastal towns of Malindi and Kilifi. Unlike Nairobi where no active dengue transmission has been reported, DF is currently re-emerging at the Coast causing major outbreaks. This study ...