Medical & Health Sciences

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Medical & Health Sciences Research Papers/Topics

Genome Sequence of a Spodoptera frugiperda Multiple Nucleopolyhedrovirus Isolated from Fall Armyworm (Spodoptera frugiperda) in Nigeria, West Africa

Abstract: We report the entire genome sequence of an isolate of Spodoptera frugi perda multiple nucleopolyhedrovirus from Nigeria, West Africa. The genome is 132,710 bp long and contains 144 open reading frames. The GC content is 40.3% and, based on bac ulovirus species demarcation criteria, the isolate belongs to the species Spodoptera frugi perda multiple nucleopolyhedrovirus.

Paenibacillus polymyxa causes yellow withered spot disease in Dracaena trifasciata in the South of China

Abstract: Mother-in-law’s tongue, Dracaena (Sansevieria) trifasciata S. is an ornamental houseplant of Asparagaceae family and native to tropical western Africa and southern Asia. Following a yellow withered spot symptom observed on up to one third of D. trifasciata plants at the field, a new bacterium pathogen was discovered for the first time in South of China. This pathogen was isolated from the early irregular yellow spot and its pathogenicity to the host plant was confirmed through ar...

Infection with tungiasis through interhost movement of adult female sand fleas, Tunga penetrans

Abstract: Tungiasis is a highly neglected tropical skin disease caused by the parasitic adult female sand flea, Tunga penetrans. More than 80% of tungiasis patients are found in the age group

Trypanosomes infection, endosymbionts, and host preferences in tsetse flies (Glossina spp.) collected from Akagera park region, Rwanda: A correlational xenomonitoring study

Abstract: Akagera National Park and its surroundings are home to tsetse flies and a number of their mammalian hosts in Rwanda. A One-health approach is being used in the control and surveillance of both animal and human try-panosomosis in Rwanda. Determination of the infection level in tsetse flies, species of trypanosomes circulating in vectors, the source of tsetse blood meal and endosymbionts is crucial in understanding the epidemiology of the disease in animals and humans in the region. ...

Pesticide pollution in freshwater paves the way for schistosomiasis transmission

Abstract: Schistosomiasis is a severe neglected tropical disease caused by trematodes and transmitted by freshwater snails. Snails are known to be highly tolerant to agricultural pesticides. However, little attention has been paid to the ecological consequences of pesticide pollution in areas endemic for schistosomiasis, where people live in close contact with non-sanitized freshwaters. In complementary laboratory and feld studies on Kenyan inland areas along Lake Victoria, we show that pest...

Bioactive constituents, in vitro radical scavenging and antibacterial activities of selected Apis mellifera honey from Kenya.

Abstract: here is limited information about the relative composition and health benefits of various honey consumed across Africa. This study aimed at estimating the bioactive constituents, in vitro radical scavenging and antibacterial activities of 16 kinds of honey obtained from different geographical locations in Kenya. Manuka 5 + honey was included for comparison. Some of the tested honey had biochemicals and bioactivities similar to or higher than Manuka 5 + honey. The honey exhibited ...

National prevalence and risk factors for tungiasis in Kenya

Abstract: Background Tungiasis is a highly neglected tropical skin disease caused by the sand fea, Tunga penetrans, the female of which burrows into the skin, causing pain and itching. The disease occurs throughout South America and sub-Saharan Africa but there are few systematic data on national disease burdens. The tungiasis research community is keen to develop survey methods to fll this gap. Here we used a school-based, thorough examination method to determine the prevalence and risk fac...

Occurrence and distribution of Nosema ceranae in honey bee colonies in the Comoros Islands

Abstract: Nosemosis is a parasitic disease caused by microsporidian pathogens of the genus Nosema infecting both the Western honey bee, Apis mellifera, and the Asian honey bee Apis cerana. The disease may adversely affect bee colonies and eventually result in high losses in apiculture and agriculture. We determined the Nosema species infecting honey bees and their prevalence in two islands of the Comoros Archipelago (Grande Comore (GCO) and Mohéli (MOH)) in the Southwest Indian Ocean. In Co...

Volatile biomarkers of symptomatic and asymptomatic malaria infection in humans

Abstract: Malaria remains among the world’s deadliest diseases, and control efforts depend critically on the availability of effective diagnostic tools, particularly for the identification of asymptomatic infections, which play a key role in disease persistence and may account for most instances of transmission but often evade detection by current screening methods. Research on humans and in animal models has shown that infection by malaria parasites elicits changes in host odors that infl...

Chemical Ecology of Animal and Human Pathogen Vectors in a Changing Global Climate

Abstract: Infectious diseases affecting livestock and human health that involve vector-borne pathogens are a global problem, unrestricted by borders or boundaries, which may be exacerbated by changing global climate. Thus, the availability of effective tools for control of pathogen vectors is of the utmost importance. The aim of this article is to review, selectively, current knowledge of the chemical ecology of pathogen vectors that affect livestock and human health in the developed and dev...

Transmission of ‘Candidatus Anaplasma camelii’ to mice and rabbits by camel-specific keds, Hippobosca camelina

Abstract: Anaplasmosis, caused by infection with bacteria of the genus Anaplasma, is an important veterinary and zoonotic disease. Transmission by ticks has been characterized but little is known about non-tick vectors of livestock anaplasmosis. This study investigated the pres-ence of Anaplasma spp. in camels in northern Kenya and whether the hematophagous camel ked, Hippobosca camelina, acts as a vector. Camels (n = 976) and > 10,000 keds were sampled over a three-year study period and the...

Small-scale field evaluation of transfluthrin-treated eave ribbons and sandals for the control of malaria vectors in rural Tanzania

Abstract: Background Early-evening and outdoor-biting mosquitoes may compromise the effectiveness of frontline malaria interventions, notably insecticide-treated nets (ITNs). This study aimed to evaluate the efficacy of low-cost insecticide-treated eave ribbons and sandals as supplementary interventions against indoor-biting and outdoor-biting mosquitoes in south-eastern Tanzania, where ITNs are already widely used. Methods This study was conducted in three villages, with 72 households parti...

Ticks (Acari: Ixodidae) infesting cattle in coastal Kenya harbor a diverse array of tick-borne pathogens

Abstract: Ticks and the microbes they transmit have emerged in sub-Saharan Africa as a major threat to veterinary and public health. Although progress has been made in detecting and identifying tick-borne pathogens (TBPs) across vast agroecologies of Kenya, comprehensive information on tick species infesting cattle and their associated pathogens in coastal Kenya needs to be updated and expanded. Ticks infesting extensively grazed zebu cattle in 14 villages were sampled and identified based o...

A cross-sectional observational study investigating the association between sedges (swamp grasses, Cyperaceae) and the prevalence of immature malaria vectors in aquatic habitats along the sho

Abstract: Background: Strategies that involve manipulations of the odour-orientation of gravid malaria vectors could lead to novel attract-and-kill interventions. Recent work has highlighted the potential involvement of graminoid plants in luring vectors to oviposition sites. This study aimed to analyse the association between water-indicating graminoid plants (Cyperaceae, sedges), other abiotic and biotic factors and the presence and abundance of early instar Anopheles larvae in aquatic hab...

Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis

Abstract: Background: Therapeutic efcacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potentially preclude/pre-empt the detection of subsequent recrudescence of persistent, sub-microscopic primary infections. Methods: Antimalarial studies typically report the risk of recrudescence derived using the Kaplan–Meier (K–M) method, which considers new infections acquired during the follow-up period...


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