Medical & Health Sciences

Research Papers/Topics in Medical & Health Sciences

Nithogen Metabolism In The Ostrich

ABSTRACTThe thriving of the ostrich in an otherwise veryharsh environment has been an intriguing question to manypeople. The objective of this study was to find out someof the physiological explanations to this question.Some aspects of nitrogen metabolism were studied inthe as trich : Major urinary nitrogen metabolites inostrich urine (uric acid nitrogen, urea nitrogen andammonia nitrogen) were partitioned. Plasma urea andurinary ammonia levels were also determined usingcommercial kits based ...

Blood Pressure To Height Ratio As A Screening Tool For Prehypertension And Hypertension In Adolescents

Background: Current methods of detection of childhood hypertension are cumbersome and contribute to under-diagnosis hence, the need to generate simpler diagnostic tools. The blood pressure to height ratio has recently been proposed as a novel screening tool for prehypertension and hypertension in some populations. We evaluated its applicability in our environment. Materials and Methods: The weights, heights, and blood pressure measurements of 2364 apparently healthy adolescents were deter...

Acute Chest Syndrome In Sickle Cell Disease Patients: Experience From A Resource Constrained Setting

AbstractBACKGROUND: Sickle cell anemia is the most common inheritable hemoglobin disorder in the world with very high prevalence, morbidity, and mortality in Sub‑Saharan Africa. Acute chest syndrome (ACS) is one of the most common causes of mortality among individuals with the condition. The management of this condition involves watchful waiting which may be deleterious in resource‑constrained settings. The use of exchange blood transfusion (EBT) has been reported to be benefici...

Knowledge And Attitudes Towards Mobile Phone Use To Promote Meternal And Child Health Among Women In Mushin Lagos State

ABSTRACT Mobile phone technology has been demonstrated to promote maternal and child health. However, its benefits are yet to be fully explored in Nigeria. The aim of this study was to determine the knowledge and attitudes towards the use of mobile phones to promote maternal and child health among, women of reproductive age group (15 - 49 years) in Mushin, Lagos, Nigeria. In this descriptive cross-sectional survey, data was collected using an interviewer-administered questionnaire fr...

Home Management Of Uncomplicated Childhood Malaria By Mothers And Fathers In Lagos State, Nigeria.

ABSTRACT Malaria is a major public health disease. About 90% of all malaria deaths globally occur in Sub- Saharan Africa where Nigeria is located. Children are particularly susceptible resulting in high mortality. Mothers stay at home to care for children with malaria, thereby increasing absenteeism resulting in economic loss at the micro and macro levels. World Health Organization (WHO) in an attempt to ensure prompt treatment of uncomplicated childhood malaria, introduced home manage...

Histomorphological Studies Of The Effects Of Amodiaquine On The Ovary In Sprague Dawley Rats

ABSTRACT The prevalence of female infertility ranges from 7 to 28% depending on the age of the woman. Although the origin and frequency of infertility vary about 40 to 50% of the aetiology of infertility cases is as a result of female factors. Malaria and the treatment of malaria have being a major challenge for decades. A number of antimalarial drugs have been reported to have anti-fertility actions. Amodiaquine (AQ) is an anti-malarial drug and belongs to a class of drugs known as th...

Histomophological And Biochemical Studies On Alloxan-Induce Diabetic Rabbits Treated With Sphenocentrum Jollyanum Menispermceae (Pierre)

ABSTRACTThe aim was to investigate the effect of Sphenocentrum jollyanum (SJ) extract on alloxan-induced diabetic and hyperglycaemic rabbits. The prophylactic effect and the hypoglycaemic activity of SJ extracts were equally evaluated. Other biochemical parameters evaluated included lipid profile. The acute and chronic toxicity tests were also conducted to ascertain the plant's toxicity level. In diabetic study, alloxan diabetic rabbits were treated with graded doses of SJ at 50,...

Hepatoxicity And Hematological Effects Of Combination First Line Antituberculosis Drugs In Healthy Sprague-Dawley Albino Rats

ABSTRACTThe commonly used antituberculosis (anti-TB) drugs, pyrazinamide (PZA), isoniazid (INH), ethambutol (EMB), and rifampicin (RMP) were administered to albino rats for the purpose of investigating the toxic consequences of combination therapies on the hematological and hepatic systems. The drugs were evaluated by simulating the normal clinical dosage. A 24-week oral administration studies of standard therapy with anti-TB drugs in albino rats without disease were carried out. The do...

Genotoxic Investigation Of Some Environmental Pollutants And Therapeutic Agents: Roles Of Antioxidants On The Mutagenicity And Toxicity Of Rifampicin

ABSTRACTThe data emerging from some of the cancer registries in sub-Saharan Africa indicate that the burden of cancer is increasing rapidly. Life style, environmental, dietary and chemical factors have all been suspected to play significant roles in the occurrence of malignancies. Rifampicin which is a first line antituberculous agent has been identified as a class three mutagen by the International Agency for Research on Cancer (IARC). Genotoxic investigation of both environmental poll...

Frequency Of Peripheral Arterial Disease Among Patients With Diabetes Mellitus Foot Syndrome In A Tertiary Hospital In Lagos, Nigeria

ABSTRACT Diabetes Mellitus Foot Syndrome (DMFS) occurs against a background infection, neuropathy and peripheral arterial disease (PAD). Clinical assessment often under diagnoses PAD. However, the use of a hand held Doppler 10 calculate the ankle brachial index (ABI) is an inexpensive, non- invasive and quantitative method of determining the presence of PAD. A retrospective analysis of patients with DMFS who had PAD assessment with a hand held Doppler was done. Data retrieved from th...

Fertility Enhancing Potential Of Aqueous Stem Extractof Cissus Populnea On The Cryptorchid Testes In Sprague-Dawley Rats

ABSTRACT Cryptorchidism is the commonest congential cause of male infertility. Male infertility is on the increase in Nigeria and current available modalities of treatment are not easily accessible but also expensive. The fertility enhancing potential of aqueous extract of the stem of Cissus populnea on the cryptorchid testes and the morphological detailing was the overall objective of this research work. One hundred and eighty male Sprague-Dawley rats were divided into twelve groups...

Evaluation Of The Pharmacological And Toxicological Actions Of Byrsocapus Coccineus Schum And Thonn (Connaraceae)

ABSTRACT The research investigated the state of maintenance management of public hospital buildings in South-west, Nigeria, and in the process, identified factors militating against their effective contribution to health care delivery. A total of 552 questionnaires comprising 206 for maintenance staff and 346 for users of public hospital buildings were collected and used for study. The survey covered 46 public hospitals representing 40% of the total number of existing public hospital...

Investigation Of Bachelor Of Science Nursing Student Performance In The Nursing Council Of Kenya Licensure Examinations In Kenya

ABSTRACTKenya has seen a drastic growth in nursing education sector recording high rates ofenrolment of students to training while their performance in Nursing Council of Kenya(NCK) examination remained variable. This study investigated performance of BScnursing students in NCK examinations by determining student characteristics,examining institutional characteristics and analyzing regulatory body characteristics inrelation to performance. NCK identified it as priority area of research. The r...

Responsiveness to HIV Education and VCT Services among Kenyan Rural Women: A Community-Based Survey.

AbstractUptake of VCT and other HIV prevention strategies among rural African women is affected by various socio-cultural and economic factors which need elucidation. Our aim was to establish the responsiveness to HIV education among rural women attending three dispensaries in Kenya. This study was designed to assess gender and psycho-social factors that influence HIV dynamics in rural Kenya. This was a cross-sectional questionnaire based study of 1347 women, conducted in October 2009. Socio-...

Effects Of “Oparanya Care Services” In Improving Skilled Delivery In Malava County Hospital Kakamega County Kenya

ABSTRACT It is estimated that nearly 300,000 women die from pregnancy related complications and childbirth. Globally 34% of deliveries take place without skilled birth attendant. In Kenya more than 50% of deliveries are conducted by unskilled persons. These high indices of maternal mortality are reason for launching incentive use and digital programme in Kakamega County commonly known as “Oparanya care services”. Despite the commitment provided by the county government in resourc...


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