Medical & Health Sciences

Research Papers/Topics in Medical & Health Sciences

Clinical effect of MTA cement for pulp capping [November 14, 2017]

Search result: 2 systematic reviews and 9 clinical trials were found.Clinical outcomes: The results suggest MTA to be effective for pulp capping.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the n...

Clinical merits of restorative treatment of root (cervical) caries lesions [November 13, 2017]

Search result: 7 trials were found.Clinical outcomes: The results suggest that various composites (nanohybrid, flowable) show good results. Etch-and-rinse adhesives appear to be superior to all-in-one adhesives, while compomers and resin-modified glass-ionomers appear to be less effective than composites.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinic...

What is the clinical longevity of lithium disilicate ceramics? [November 24, 2017]

Search result: 5 trials and 6 systematic reviews were found. .Clinical outcomes: The results suggest that:(i) for lithium disilicate single crowns, the existing evidence indicates excellent short-term survival rates, but the evidence for medium-term survival is limited;(ii) for lithium disilicate fixed dental prostheses, the evidence for short-term survival is fair, although limited, but the evidence for medium-term survival is not promising;(iii) there is contradicting evidence whe...

Have stannous ions any remineralising effect on dental tissues? (Therapeutic) [November 11, 2017]

Search result: 11 trials were found.Clinical outcomes: The results suggest that stannous ions may have a caries/demineralisation preventive effect (particularly when stannous fluoride was compared to sodium fluoride).[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessmen...

Have stannous ions any remineralising effect on dental tissues? (Therapeutic) [November 10, 2017]

Search result: 5 trials were found.Clinical outcomes: The results of the laboratory trials appear contradictory particularly when stannous fluoride was compared to sodium fluoride).[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity...

Have stannous ions any antibiotic effect on oral bacteria? [November 9, 2017]

Search result: 9 trials were found.Clinical outcomes: The results of the mainly laboratory trials suggest that stannous ions have an inhibiting effect on oral bacteria (particularly when stannous fluoride was compared to sodium fluoride).[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as ...

Has zinc any antibiotic effect on oral bacteria? [November 8, 2017]

Search result: 13 trials were found.Clinical outcomes: The results of the mainly laboratory trials suggest that zinc has an inhibiting effect on oral bacteria.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not...

What are the clinical merits of chemically cured glassionomers (GIC) for placing cervical tooth restorations? [November 07, 2017]

Search result: Only trials with low-viscosity GIC were found.Clinical outcomes: The results suggest that cervical restorations placed with chemically cured GICs have good survival rates when compared to composite but are less aesthetic.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as we...

Potential of adverse effects due to aluminium, barium and strontium in GIC [November 06, 2017]

Search result: No clinical evidence concerning adverse effects of aluminium, barium or strontium released from GICs were found.Clinical outcomes: A review of the relevant laboratory literature, including a conservative calculation of any potential adverse clinical effect due to aluminium content, concludes that the amount of aluminum that could be leached into the body from glass-ionomer dental fillings is well below the permitted daily dose and almost certainly too small to ha...

What are the clinical differences between HVGIC restorations placed after handmix or capsule mix? [November 05, 2017]

Search result: Three articles could be found.Clinical outcomes: Capsule mixed HVGIC restorations appear to be superior to that of hand mixed. The quality of the existing evidence requires further assessment.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of preci...

What is the failure rate of GIC restorations placed after incomplete removal of infected carious dentine? [November 04, 2017]

Search result: Two clinical controlled trials were found.Clinical outcomes: The results suggest no difference in the failure rate of GIC restorations placed after either complete or incomplete removal of infected (soft) carious dentin.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as wel...

What is the recent evidence that merit composite resin for direct tooth restorations (as compared to amalgam as current gold standard)? [November 03, 2017]

Search result: Four clinical controlled trials were found.Clinical outcomes: The results show that composite resin performs less satisfactory when compared to amalgam. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results a...

What effect has CPP-ACP on the plaque pH? [October 31, 2017]

Search result: One article, reporting on 2 clinical trials, was identified, concerning plaque pH-decrease after sucrose challenge: (a) comparison of CPP-ACP containing paste with no paste; (b) comparison of CPP-ACP containing paste with placebo.Clinical outcomes: The results show a significant reduction in plaque pH fall after sucrose challenge with CPP-ACP containing paste. The results of both reported trials need to be regarded with caution due to: unclear reporting of study&...

What effect has CPP-ACP on the salivary pH? [October 30, 2017]

Search result: No clinical trials or 2-arm (controlled) trials of any design (in-situ, in-vitro) could be found. Only one singlearm/longitudinal in-situ trial was identified. This trial used the test subjects as control group (without CPP-ACP).Clinical outcomes: The results of this trial showed an increase of the saliva pH in 16 out of 25 subjects after 3 weeks. A change from the initial level of pH 6.6 to the final level of around pH 7.6 was observed.[‘Preliminary Systematic Literatur...

How do both Strontium and calcium-based GIC compare clinically? [October 29, 2017]

Search result: Ten clinical trials were found and traced concerning high-viscosity conventional GIC. No trials were identified comparing strontium or calcium low-viscosity conventional GIC. All identified trials compared Fuji IX for strontium and Ketac Molar for calcium based GIC.Clinical outcomes: The overall results suggest no difference between Fuji IX and Ketac Molar in the clinical outcomes of: recurrent caries, occlusal wear and colour match. Two of the 10 trials suggest ...


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