Medical & Health Sciences

Research Papers/Topics in Medical & Health Sciences

MI Paste PLUS effect to prevent white spot lesions associated with orthodontic treatment [October 25, 2016]

Search result: Three contradicting clinical trials were found so far.Clinical outcomes: Some results show that MI Paste Plus appears more effective in reducing white spot lesions than placebo and fluoride varnish after 3 months, while other results suggest that its effect appears to be equal to that of normal home care after 2 months. The quality of the existing evidence requires further assessment.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic sy...

Etch-rinse systems with and without selective enamel etching [October 25, 2016]

Search result: 4 clinical trials were found.Clinical outcomes: The results indicate that additional selective enamel etching does not improve the clinical performance of restorations. The quality of the existing evidence requires further assessment.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases se...

Selective enamel etching effect on clinical performance of selfetch / self-adhesive systems [October 24, 2016]

Search result: 15 clinical trials were found.Clinical outcomes: Minor or no improvements are reported when selective enamel etching was used. Selective enamel etching may not pose a hazard in terms of postoperative hypersensitivity. The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searc...

Advantages of Self-etch versus Etch-and-rinse systems [October 24, 2016]

Search result: Nine articles reporting on 4 clinical trials after different follow-up periods were found.Clinical outcomes: The results indicate no difference in retention and anatomic form of restorations after 1 – 3 years. Marginal adaptation appears to be superior for etch-and-rinse systems after 1 – 2 years and no difference was found after 3 years. Marginal discoloration is significantly more observed for (1-step) self-etch systems. Post-operative sensitivity was the s...

Resin infiltration to stop carious lesion progression [October 23, 2016]

Search result: Nine clinical studies were found.Clinical outcomes: The results suggest efficacy of resin-infiltration technique to stop caries progression and to improve aesthetic appearance of white spot lesions (WSL). However, discomfort levels appear to be higher than with other noninvasive interventions.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing cli...

Anticaries effect of CPP-ACP [October 20, 2016]

Search result: As the topic of CPP-ACP is of high-priority a more intensive systematic literature search was conducted in order to produce this evidence sheet. 22 clinical studies were found. In-situ studies, as well as studies including ACP/casein materials not covered by the Recaldent technology, as included in the original systematic review, were not included.Clinical outcomes: Preventive effect: The results regarding the clinical efficacy of CPP-ACP in the prevention and&nb...

GIC versus RM-GIC as fissure sealant [October 18, 2016]

Search result: Only one clinical study was found.Clinical outcomes: The results indicate no difference in the caries preventive effect between both materials as fissure sealants in permanent teeth. The retention rate of RM-GIC in pits and fissures was higher than for conventional GIC.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limite...

Fluoride release of resin-modified GIC versus fluoride containing composite resin [October 18, 2016]

Search result: Only two clinical studies were found.Clinical outcomes: The results indicate that GICs release more fluoride under clinical conditions than fluoride containing composite resin.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and interna...

Fluoride release of resin-modified GIC versus Compomers [October 17, 2016]

Search result: Two clinical studies were found.Clinical outcomes: The results indicate a higher fluoride concentration in plaque surrounding teeth that were either bonded or restored with resin-modified GIC than with compomer.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the ...

Longevity of conventional GIC versus compomers in primary teeth [October 17, 2016]

Search result: Four clinical studies concerning restorations were found.Clinical outcomes: The results indicate no difference in the success rate between both types of material if high-viscosity GIC was compared against Compomers.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as ...

Survival rate of ART restorations with high-viscosity GIC versus conventional RM-GIC [October 14, 2016]

Search result: Only two clinical studies concerning restorations were found.Clinical outcomes: The results indicate no difference in the survival rate after 12 and 24 months.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results ...

Retention of conventional GIC versus RM-GIC restorations [October 14, 2016]

Search result: There is still a lack of studies to this topic and only two clinical studies concerning restorations were found.Clinical outcomes: The results indicate no difference in the retention rate after 12 and 42 months in Class V and Class II restorations, respectively.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited i...

The current evidence for caries prevention and treatment in xeriostomic patients [October 12, 2016]

Search result: Ten controlled clinical studies relevant to the topic were found.Clinical outcomes: The results indicate:- GIC/RM-GIC has higher caries-preventive effects than composite/amalgam in cases were no additional fluoride was provided to patients have been shown;- Topical fluoride is indicated as caries-preventive;- Mineral containing supplements, with and without casein appear to be at least as effective as topical fluoride in caries prevention;- The effect of Chlorhexidine...

Retention of GIC versus Amalgam as restorations [October 12, 2016]

Search result: There is still a lack of studies to this topic and only two clinical studies concerning restorations in the primary dentition were found.Clinical outcomes: The results of (conventional) high-viscosity GIC indicate no difference to amalgam while, low viscosity GIC perform significantly worse than amalgam.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over e...

Longevity of resin-modified GIC versus compomers in primary teeth [October 11, 2016]

Search result: Only three clinical studies were found.Clinical outcomes: The results indicate no difference in the longevity between both types of materials.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not r...


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