Medical & Health Sciences

Research Papers/Topics in Medical & Health Sciences

How differ coated high-viscosity GIC restorations (i.e. EQUIA) from non-coated in clinically relevant aspects? [October 10, 2016]

Search result: Three prospective clinical controlled trials were found.Clinical outcomes: The results indicate that there may be a trend that coating can protect Fuji IX GP Extra against wear.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal va...

Cariostatic effect of conventional GIC versus compomers [October 08, 2016]

Search result: There is a lack of clinical studies to this topic: Only three clinical trials were found and traced.Clinical outcomes: The results are conflicting or suggest no difference between conventional GIC and Compomers in regard to their anticariogenic effects.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number o...

Cariostatic effect of resin-modified GIC (RM-GIC) versus compomers [October 08, 2016]

Search result: Twelve clinical trials were found and traced.Clinical outcomes: The overall results suggest no difference between RM-GIC and Compomers in regard to their anticariogenic effects.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and intern...

Antibacterial effect of GIC versus composite resin [October 04, 2016]

Search result: One clinical trial was found and traced concerning resin-modified GIC (RM-GIC). The material was Fuji II LC (compared to: Tetric Flow and Helioseal F). No trials were identified comparing conventional GIC (C-GIC) with composite resin.Clinical outcomes: The overall results suggest a higher antibacterial effect for RM-GIC up to 6 months.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature an...

Have Stannous ions Any Remineralising Effect on Dental Tissues? (Therapeutic)

Search result: 2 trials were found.Clinical outcomes: The results of the laboratory trials suggest that stannous ions have a remineralising (therapeutic) effect on dental tissue (particularly when stannous fluoride was compared to sodium fluoride).[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as we...

Has Zinc Any Antibiotic Effect on Oral Bacteria?

Search result: 12 trials were found.Clinical outcomes: The results of the mainly laboratory trials suggest that zinc has an inhibiting effect on oral bacteria.State of evidence and recommendations: The quality of the existing evidence requires further assessment.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases s...

What are the Clinical Merits of Chemically Cured Glass-ionomers (GIC) for Placing Cervical Tooth Restorations?

Search result: Only trials with low-viscosity GIC were found.Clinical outcomes: The results suggest that cervical restorations placed with chemically cured GICs have good survival rates when compared to composite but are less aesthetic.State of evidence and recommendations: The quality of the existing evidence requires further assessment.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews...

Potential of adverse effects due to aluminium, barium and strontium in GIC

Search result: No clinical evidence concerning adverse effects of aluminium, barium or strontium released from GICs were found. A review of the relevant laboratory literature, including a conservative calculation of any potential adverse clinical effect due to aluminium content, concludes that the amount of aluminum that could be leached into the body from glass-ionomer dental fillings is well below the permitted daily dose and almost certainly too small to have a measurable effect. This,...

What are the clinical differences between HVGIC restorations placed after handmix or capsule mix?

Search result: No trial could be found.Clinical outcomes: NoneState of evidence and recommendations: None[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]

Have stannous ions any antibiotic effect on oral bacteria?

Search result: 7 trials were found.Clinical outcomes: The results of the mainly laboratory trials suggest that stannous ions have an inhibiting effect on oral bacteria (particularly when stannous fluoride was compared to sodium fluoride).State of evidence and recommendations: The quality of the existing evidence requires further assessment.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overvie...

What is the failure rate of GIC restorations placed after incomplete removal of infected carious dentine?

Search result: Two clinical controlled trials were found.Clinical outcomes: The results suggest no difference in the failure rate of GIC restorations placed after either complete or incomplete removal of infected (soft) carious dentin.State of evidence and recommendations: The quality of the existing evidence requires further assessment.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews ...

What is the recent evidence that merit composite resin for direct tooth restorations (as compared to amalgam as current gold standard)? [November 19, 2015]

Search result: Four clinical controlled trials were found between the period of 2004 and 2015 (19.11.15).Clinical outcomes: The results show that composite resin performs less satisfactory when compared to amalgam.State of evidence and recommendations: The quality of the existing evidence requires further assessment.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clin...

What effect has CPP-ACP on the salivary pH?

Search result: No clinical trials or 2-arm (controlled) trials of any design (in-situ, in-vitro) could be found. Only one single-arm/longitudinal in-situ trial was identified. This trial used the test subjects as control group (without CPP-ACP).Clinical outcomes: The results of this trial showed an increase of the saliva pH in 16 out of 25 subjects after 3 weeks. A change from the initial level of pH 6.6 to the final level of around pH 7.6 was observed.State of evidence and recommendations:...

How do both Strontium and calcium-based GIC compare clinically? [November 13, 2015]

Search result: Ten clinical trials were found and traced concerning high-viscosity conventional GIC. No trials were identified comparing strontium or calcium low-viscosity conventional GIC. All identified trials compared Fuji IX for strontium and Ketac Molar for calcium based GIC.Clinical outcomes: The overall results suggest no difference between Fuji IX and Ketac Molar in the clinical outcomes of: recurrent caries, occlusal wear and colour match. Two of the 10 trials suggest ...


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