ABSTRACT Eukaryotic pathogens are responsible for several serious human diseases, however, most drugs used as treatment regimens are ineffective while others still in use are toxic. This study seeks to identify bioactive molecules from wood decay fungal (WDF) extracts with activity against eukaryotic pathogens (especially Candida albicans and Plasmodium falciparum). The Saccharomyces cerevisiae model organism for eukaryotic cell biology studies is extensively used to screen bioactive molecul...
ABSTRACT This is thesis was done based on the textural, mineralogical and mineral chemistry studies of arc rocks from the North Island of New Zealand. The rocks in the area are of two main groups: the Kiwitahi and Coromandel groups. Both the Coromandel group and Kiwitahi andesites are typically porphyritic with a phenocryst assemblage (20–60%) consisting of plagioclase + pyroxene + Fe –Ti-oxide in a granular groundmass rich in plagioclase laths and pyroxene microcrystals. The Kiwitahi sa...
ABSTRACT Road traffic injuries among motorcyclists worldwide have persisted as a serious public health problem with much of the health burden in the developing countries especially the middle and low-income countries. This problem has not excluded Ghana which continually suffers from road traffic injuries and fatalities mainly caused by over speeding, non-adherence to road safety regulations (helmet usage) and poor enforcement of traffic regulations. The main aim of the study was to determin...
ABSTRACT The goal of preserving biodiversity for the benefit of present society and posterity have driven the creation of Protected Areas (PA) across the world. Yet, satiating conservation and protecting livelihoods of local people have been a challenge to protected area management. The incentive to protect livelihoods and avoid alienation from PAs have led to local people’s indulgence in illegal activities. This pose risks to the very survival of PAs. Like other parts of the world, PAs in...
Abstract The distribution, nesting habits and activity as well as seasonal population pattern of Camponotus acvapimensis Mayr were studied in a savanna area of Ghana* The ants were distributed in the poor shaded areas of the savanna grassland* Type of soil, light and food availability were found to influence the nesting and anti’s distribution. Analysis for preference of nesting sites indicated that the ants nest in the soil or grass roots but where wood is available, the bark formed a ve...
ABSTRACT This study proposes a method for classification based on a Pattern Trace Network and Principal Component Analysis. Using data from a public Senior High School, the proposed method was applied to forecast whether or not a Senior High School (SHS) student would qualify for admission into the university. The method’s performance and the performance of Logistic Regression were compared. The independent variables used in the study are gender, boarding status, program of study, and cont...
ABSTRACT The Ghanaian ecosystem plays host to various lagoons which serve different purposes. The most important of them is being home for different types of fish species. Examples are Sarotherodon melanotheron (Cichlidae) which is popularly called blackchin tilapia and Tilapia guineensis (Bleeker) also known as redchin tilapia. Quality assessment was done to ascertain the level of pollution in water and sediment samples from Sakumo, Chemu and Kpeshie lagoons. Physicochemical parameters (pH,...
ABSTRACT Cerebral malaria occurs due to abnormality in the function of the brain endothelium. This signifies that the brain endothelium plays a crucial role in the outcome of malaria in children. Regulated balance between angiopoietin-1 and angiopoeitin-2 is responsible for the control of normal endothelial cell function. The angiopoietin-Tie-2 system has been shown to regulate endothelial cell function and vascular integrity. Endothelial Protein C Receptor (EPCR) and Thrombomodulin (TM) are...
ABSTRACT Bats are nocturnal mammals found everywhere except in the Antarctica and Arctic regions. They are important for the maintenance of the ecosystem in terms of pollination and seed dispersal, particularly in tropical regions, as well as in controlling insect populations that would otherwise be pests. Bats have been reported as reservoir hosts for several pathogens including viruses such as Ebola, Nipah, Hendra and Lyssa. The purpose of the study was to document the parasites that infes...
ABSTRACT This thesis provides an assessment of the effectiveness of the National Health Insurance Scheme (NHIS) in Ghana implemented by Act 650 and L.I 1809, 2004. This assessment is done by taking the Akuapem South Mutual Health Insurance Scheme, selected health facilities in the NsawamAdoagyiri Municipality and Akuapem South District that provides health insurance services and health insurance users as case study. The selected health facilities are the Nsawam Government Hospital, Pokrom H...
ABSTRACT Education is at the heart of development. Educating her citizenry is one of the burdens of the government over the past years. Falling standards of education in Ghana has brought about an implementation of an educational policy known as the Free Compulsory Universal Basic Education (FCUBE) Programme by the Ghana Government. This bold educational policy had resource implications. It is against this background that Ghana Government solicited for assistance from external sources. The A...
ABSTRACT A very good reason why calculation of dose distribution is important is that it is essential to plan and replicate the treatment prior to the actual delivery of the radiation dose to the tumour. In modern radiation therapy, computer software is used for performing treatment planning. Different algorithms are employed at every stage of treatment including dose calculation algorithms. The dose calculation used for the HDRplus TPS is the TG43 formalism and just like every other TPS, th...
ABSTRACT Oryza glaberrima is a local rice variety that is native to West Africa. Its tough texture androbustness produces milled rice with a large quantity of broken grains when dehusked (polished) accounting for the huge gap in quality. Consequently, imported rice is much more consumed inGhana than locally cultivated and milled rice. The objective of this study was to add value tolocal rice by developing and characterizing a rice-based baby food from low grade locally milledand parboiled ri...
ABSTRACT Plasmodium falciparum gametocytes are able to infect the mosquito even at levels below microscopic detection and are responsible for malaria transmission. Gametocytes are exposed to immune pressure from the host and as a result, the host is able to develop antibodies against these gametocytes. However, it has not been determined whether naturally acquired immune response against gametocytes have a direct correlation with the presence of sub-microscopic gametocytes in the peripheral ...
ABSTRACT Ghana like most developing countries is undergoing a rapid population growth and this affects and limits the effectiveness of environmental structures. Cholera epidemics have been an ‘annual ritual’ and communities within the Greater Accra Metropolitan Area (GAMA) record the highest number of cases. This study assesses the households’, communities and local governments’ preparedness and response to cholera epidemics in indigenous communities in La and Chorkor. The research u...