ABSTRACT The natriuretic peptide systems also affect blood pressure through its vasodilatory and natriuretic activities generating interest in its role in the development of hypertension. The polymorph isms of the ANP have been investigated in different populations but similar studies i are not documented for Nigerian populations. The study investigate the association of -C664G allele of the ANP gene and hypertension in residents of Calabar and Uyo, Nigeria. The study involved 1308 participan...
ABSTRACT The characteristics of the post-junctional -adrenoceptors in the isolated anococcygeus muscle and vas deferens were compared in spontaneously hypertensive rats (SHR) and normotensive rats (NCR), Responses to CK —adrenoceptor agonists were obtained in the absence and presence of cocaine and of antagonists, Noradrenaline I (NA) and phenylephrine (PE) produced concentration related contractions of the preparations which were antagonised by phentolamine5 prazosin and yohimbine in both ...
ABSTRACT Reporting of notifiable diseases is essential for control and prevention of outbreak of diseases. In Nigeria, reporting of Notifiable Diseases by health workers has not been adequately documented. This study was conducted to assess health workers knowledge, practices, and factors influencing disease reporting in urban and rural communities in Oyo State, Nigeria. A cross-sectional survey was carried out among the 210 health workers who were responsible for disease reporting at their ...
ABSTRACT There is a dearth of information on the reference values for haematological indices particularly according to the relevant trimesters of pregnant women in Nigeria. The objective of this study was to provide reference values for Nigerian pregnant women. The study took place at the Adeoyo Maternity Hospital and the University College Hospital, both in Ibadan. This descriptive study was carried out over a period of 8 months. Subjects were apparently healthy pregnant women that satisfied...
ABSTRACT The purpose of the study was to explore the nursing care experiences of in-patient older adults in the Cape Coast Metropolis of the Central Region of Ghana. The study employed a qualitative research approach with a descriptive design and recruited sixteen older adults of ages 60 years and above. The findings of this study showed five major themes, namely: physical, physiological, psychological, social nursing care experiences; as well as the perception of older adults about their nu...
ABSTRACT Though contraceptive knowledge has become widespread among Female Adolescents in Ghana, its use has persistently remained low for which the Central Region is no exception. Several studies have shown no evidence of empirical study conducted on Adolescents knowledge, Access and Usage of contraceptives among female adolescents in the Cape Coast Metropolis. To fill this literature gap, this study assessed the Adolescents knowledge level of contraceptive usage, the availability and acces...
ABSTRACT The purpose of this study was to explore the management and coping strategies of hypertensive patients seeking treatment at Brong Ahafo Regional Hospital, and to examine participants’ experiences of living with the condition. A mixed method design was used and all 508 consenting patients were selected for the quantitative aspect, and 16 were conveniently sampled for the qualitative one. Instruments (questionnaire and in-depth interview guide) derived from five pre-existing ones wer...
ABSTRACT The disability caused by stroke could lead to significant decline in the level of functioning and deterioration of quality of life (QoL). QoL assessment could be used to evaluate the impact of stroke, assist in planning effective treatment, appraise efficacy of stroke rehabilitation, and evaluate cost effectiveness in order to justify expenditures on health care. This article reviewed the QoL of Nigerian stroke survivors and also identified its determinants. More than 70% of the stu...
ABSTRACT The constellation of laboratory and imaging findings that distinguish progressive chronic kidney disease (CKD) from acute renal failure are bilaterally small kidneys, elevated PTH, creatol, carbamylated haemoglobin levels; anaemia, hyperphosphataernia and hypocalcemia with elevated parathyroid hormone levels, and a urinary sediments that reveal proteinuria and broad casts. There has been a documented significant correlation between renal length and GFR, but, the relationship between ...
Background: Radiation protection in paediatric radiology requires special attention than in adult because children are mare sensitive to radiation and at higher risk. This risk is explained by the longer life expectancy in children which allows for harmful effects of radiation to manifest and their developing organs and tissues being more sensitive to radiation. Hence, the need for determination of appropriate radiation dose for paediatric patients. Aims: To estimate entrance skin dose (ESD)...
ABSTRACT Meat and offal obtained from cattle and goats sold in open markets serve as sources of protein, but may be susceptible to heavy metal contamination due to illicit disposal and emission in the environment. Consumers‘ knowledge on the possible exposure to heavy metal contamination in meat and its associated health risks is low. Therefore, this study aimed at assessing heavy metal levels in these products. A cross-sectional study design with observational and laboratory analysis comp...
ABSTRACT The study aimed to determine the maternal characteristics and contribution to obstetric morbidity of infants presenting with fetal macrosomia at the University College Hospital, Ibadan. This was a retrospective study. Obstetric data of the mothers were extracted from the casenotes and analysed. Fetal characteristics such as sex and weight, and perinatal complication were also analysed. The maternal characteristics that were significantly different in the study and control groups were...
ABSTRACT Chlorhexidine gluconate(CHG) is a popular disinfectant/antiseptic which is often formulated with additives. We investigated the effect of additives type on the in vitro bactericidal kinetics of CHG in three commercially available formulations: Hibiscrub®, Savlon® and Purit® commonly used as household and hospital disinfectants/antiseptics. The bactericidal kinetics of the products was determined by time-survival curve method using Pseudomonas aeruginosa NCTC 6750 and Staphylococc...
ABSTRACT Background: Individuals living with diabetes mellitus are at an increased risk of developing foot ulcers and cardiovascular complications or a neuropathy that may result in amputations. These complications have been shown to be already present in about 10% of diabetic patients at the time of diagnosis. Objectives: This study was carried out to determine the level of awareness and attitude to foot care among adult diabetic patients attending a university health centre (i.e. a primary...
ABSTRACT This study evaluated the effect of an AIDS education program on deaf secondary school students' knowledge, attitude and perceived susceptibility to AIDS using peer education. Two secondary schools matched fur ownership (government), composition (mixture of hearing and deaf and teaching arrangement (separate teaching of deaf students using sign language) were used, and each school was randomly allocated the intervention or control status. All students completed a questionnaire on AIDS...