Medical & Health Sciences

Research Papers/Topics in Medical & Health Sciences

What are the clinical merits of chemically cured glass-ionomers (GIC) for placing cervical tooth restorations? [November 21, 2016]

Search result: Only trials with low-viscosity GIC were found. The results suggest that cervical restorations placed with chemically cured GICs have good survival rates when compared to composite but are less aesthetic.Clinical outcomes: The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic s...

Potential of adverse effects due to aluminium, barium and strontium in GIC [November 19, 2016]

Search result: No clinical evidence concerning adverse effects of aluminium, barium or strontium released from glassionomer cements (GICs) were found.Clinical outcomes: A review of the relevant laboratory literature, including a conservative calculation of any potential adverse clinical effect due to aluminium content, concludes that the amount of aluminum that could be leached into the body from glass-ionomer dental fillings is well below the permitted daily dose and almost ce...

What are the clinical differences between HVGIC restorations placed after handmix or capsule mix? [November 19, 2016]

Search result: Three articles could be found.Clinical outcomes: Capsule mixed HVGIC (high-viscosity glass-ionomer cement) restorations appear to be superior to that of hand mixed. The quality of the existing evidence requires further assessment. The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic sys...

What is the failure rate of GIC restorations placed after incomplete removal of infected carious dentine? [November 18, 2016]

Search result: Two clinical controlled trials were found.Clinical outcomes: The results suggest no difference in the failure rate of GIC restorations placed after either complete or incomplete removal of infected (soft) carious dentin. The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic se...

What is the recent evidence that merit composite resin for direct tooth restorations (as compared to amalgam as current gold standard)? [November 18, 2016]

Search result: Four clinical controlled trials were found between the period of 2004 and 2015 (19.11.15).Clinical outcomes: The results show that composite resin performs less satisfactory when compared to amalgam.The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental&n...

What effect has CPP-ACP on the plaque pH? [November 16, 2016]

Search result: One article, reporting on 2 clinical trials, was identified, concerning plaque pH-decrease after sucrose challenge: (a) comparison of CPP-ACP containing paste with no paste; (b) comparison of CPP-ACP containing paste with placebo.Clinical outcomes: The results show a significant reduction in plaque pH fall after sucrose challenge with CPP-ACP containing paste. The current level of clinical evidence to this topic is still limited in quantity and quality and more t...

What effect has CPP-ACP on the salivary pH? [November 16, 2016]

Search result: No clinical trials or 2-arm (controlled) trials of any design (in-situ, in-vitro) could be found. Only one singlearm/longitudinal in-situ trial was identified. This trial used the test subjects as control group (without CPP-ACP).Clinical outcomes: The results of this trial showed an increase of the saliva pH in 16 out of 25 subjects after 3 weeks. A change from the initial level of pH 6.6 to the final level of around pH 7.6 was observed. The current level of clinical ...

How do both Strontium and calcium-based GIC compare clinically? [November 15, 2016]

Search result: Ten clinical trials were found and traced concerning high-viscosity conventional GIC. No trials were identified comparing strontium or calcium low-viscosity conventional GIC. All identified trials compared Fuji IX for strontium and Ketac Molar for calcium based GIC.Clinical outcomes: The overall results suggest no difference between Fuji IX and Ketac Molar in the clinical outcomes of: recurrent caries, occlusal wear and colour match. Two of the 10 trials suggest ...

Pulp response conventional GIC versus Calcium hydroxide (CaOH) cement [November 15, 2016]

Search result: Three clinical trials with a laboratory component were found.Clinical outcomes: There appears to be no difference in the pulp response between conventional GIC and CaOH-cement (CaOH is considered to be the gold standard in pulp treatment due to its high tissue supporting properties. Lack of difference between C-GIC and CaOH suggest high biocompatibility of C-GIC concerning pulp tissue).The current level of clinical evidence to this topic is still limited in quant...

NEUTRALIZATION OF THE LETHAL EFFECT OF BITIS ARIETANS VENOMBY EUPHORBIA COTINIFOLIA LEAF EXTRACT

TABLE OF CONTENTSCONTENTS PAGETITLE PAGE - - - - - - - - - iDECLARATION - - - - - - - - iiCERTIFICATION - - - - - - - - iiiDEDICATION - - - - - - - - ivACKNOWLEDGEMENT - - - - - - - vTABLE OF CONTENT - - - - - - - viLIST OF TABLES - - - - - - - - ixLIST OF FIGURES - - - - - - - ixABSTRACT - - - - - - - - - xCHAPTER ONEINTRODUCTION AND LITERATURE REVIEW1.1 TRADITIONAL MEDICINE - - - - - - -11.2 MODERN MEDICINE - - - - - - - -41.2.1 The Role of Plants in Drug Development - - - - -41.3 DES...

Survival rate of restorations with GIC cavity liners versus GIC restorations [November 13, 2016]

Search result: One clinical trial was found.Clinical outcomes: There appears to be no difference in the success rate of both types.The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limit...

Survival rate of restorations with GIC cavity liners versus restorations with no-GIC liners [November 13, 2016]

Search result: Five clinical trials were found.Clinical outcomes: There appears to be no difference in the survival rate of both types of restorations. Post-operative sensitivity appears to be reduced for a short-time period after restoration placement when a GIC liner is used.The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.[‘Preliminary Systematic Literature Searches’...

Restoration longevity of conventional high - viscosity GIC restorations versus direct composite filings [November 12, 2016]

Search result: Two clinical trials were found.Clinical outcomes: There appears to be no difference in the survival rate of both types of restorations after 2 years. The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over e...

Failure rates of direct composite versus GIC/Composite sandwich restorations [November 12, 2016]

Search result: Four clinical trials were found. The limited number of clinical trials is surprising considering that the topic of GIC/Composite sandwich restorations was very popular 20 years ago. However, the bulk of research studies appeared to be limited to a very large number of laboratory (in-vitro) trials, only. Although important to clarify material characteristics, laboratory trials are unable to provide information how well these restorations really perform in the&nbsp...

MI Paste PLUS effect to prevent white spot lesions associated with orthodontic treatment [October 25, 2016]

Search result: Three contradicting clinical trials were found so far.Clinical outcomes: Some results show that MI Paste Plus appears more effective in reducing white spot lesions than placebo and fluoride varnish after 3 months, while other results suggest that its effect appears to be equal to that of normal home care after 2 months. The quality of the existing evidence requires further assessment.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic sy...


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